Example: chemical warfare agents

The Chemical Weapons Convention (CWC) prohibits the development, production, acquisition, stockpiling, retention, transfer or use of chemical weapons. It also contains a comprehensive reporting and inspection system for production, processing, consumption and trade in chemicals that are known to be capable of misuse in the production of chemical weapons. The substances are divided into three lists according to risk and industrial importance: the higher the potential for misuse and the lower the civil industrial use potential, the more restrictive the regulation. The CWC is monitored by the Organisation for the Prohibition of Chemical Weapons (OPCW).
The lists define single substances as well as groups of substances that are similar in structure and mode of action but are not listed individually (by name or registration number), e.g., in list 1A1:O-alkyl alkylphosphonofluoridates.

An aggravating factor is that although some of these substances are highly toxic, they often do not have a hazardous substance classification due to the trade ban, as the classification is linked to trade in the chemical. The substances for which no hazard classification is known, but which correspond to the structural definitions of a CWC list, are assigned to the corresponding list by the system. Depending on the list, additional hazard classifications are made by the system:  Substances that can be assigned to list 1A are classified by the system with the hazard pictogram GHS06 (skull and crossbones) and the signal word "Danger", as well as the H- phrases H300, H310, H330. Substances which are assigned to list 2A are classified by the system with the hazard pictogram GHS06 (skull and crossbones) and the signal word "Danger", as well as the H-phrase H300.
Classifications made by the system may not be complete and will show the comment "incomplete hazard information calculated from structure".
Isotope-labelled and stereoisomers are also taken into account, according to an opinion of the Scientific Advisory Board (SAB) of the OPCW.

Example: Amiton

Amitone (systematic name: O,O-diethyl-S-[2-diethylaminoethyl]thiophosphate) is also known as VG or tetram. It is a chemical warfare agent listed in Schedule 2A1 of the Chemical Weapons Convention.

Although the substance is known and therefore an entry exists in the SciDex database, neither pictograms nor H-phrases are defined by distributors. Since the database entry refers to the relevance of the CWC for this substance, the OBW system assigns the pictogram GHS06 (skull and crossbones) and the H-phrase 300 here. The comment "incomplete hazard information calculated from structure" indicates that the classification was made by the system and may not be complete.

Result:

All information without guarantee!