Completed Master's Theses
2024
- Patricia Budimir: Synthese von antitumoralen γ-asymmetrischen dialkylierten-TriPPPro-Verbindungen
- Melanie Kock: Total synthesis of a lipophilic and photo-labile masked NAADP derivative
- Lara Prilop: Synthese von 4‘-Fluoruridin-Nucleotid-Prodrugs und DHODH Inhibitoren als potentielle Wirkstoffe gegen hämorrhagische Fieberviren
2023
- Celine Fischer: Synthese Octanoyloxybenzyl-maskierter caged-ADPR-Derivate
- Elmar Surin: Synthese von All-In-One-Clickable-NAADP-Derivaten
2022
- Patrick Knäbe: Synthese von strukturmodifizierten N-Hydroxycytidinen als potentielle anti-SARS-CoV-2-Inhibitoren
- Alja Corinna Wölk: Synthese von antitumoralen TriPPPro-Prodrugs
- Jan Iven Henry Knaack: Synthesis of cytidine-based TriPPPro-compounds and tetrazine-fluorophore conjugates for bioorthogonal fluorescent labelling of nucleic acids
Lydia Gerber: Synthese und Evaluation potentieller pharmakologischer Chaperone zur Therapie von Medium-Chain-Acyl-CoA-Dehydrogenase-Defizien
2022
- Patrick Knäbe: Synthesis of structurally modified N-hydroxycytidines as potential
anti-SARS-CoV-2-inhibitors
2021
- Sahra Tajdar: Contributions to the synthesis of a luorescently labelled ADP-ribose
2020
- Sarah Post: Synthesis of a lipophilically masked building blocl to generate a NAADP analogue
- Vanessa Meyen: Synthesis of fluorescent chemosensors for the detection of adenosine triphosphate on cell surfaces
- Desiree Rijono: Synthesis and Optimization of DHODH-Inhibitors as Potential Drugs against Bunyaviruses
- Melanie Hofmann: Synthesis of a chemically stabilized, lipophilically masked nicotinic acid nucleotide analogue as building block for the total synthesis of NAADP derivatives
- Benedikt Ganter: Synthesis of Modified T-1106-Triphosphate Prodrugs as Potential Antiviral Drugs
2019
- Tobias Schneider:Contributions to the synthesis of lipophilic and photolabile ADPR
- Julian Witt: Synthesis of fluorescence labeled TriPPPro-compounds for cellular uptake studies and synthesis of antitumoral TriPPPro-Compounds
- Giuliano Kullik: Synthesis of phosphonate diphosphate prodrugs
2018
- Janina Krügel: Synthesis of cyclopropene derivatives for the synthesis of TriPPPro-compounds for the use in bioorthogonal chemistry
2017
- Vincente Sterrenberg: Synthesis of VU and VdU TriPPPro-compounds for cellular DNA/RNA-imaging
- Oliver Kardell 5-Vinyl-2'-deoxyuridine & 5-Vinyluridine - attractive target compounds for combining the TriPPPro-approach and bioorthogonal chemistry for a potential application in nucleic acid labeling
- Jonas von Bargen Beitrag zur Synthese von 2-Alkyl-4-(hydroxymethyl)phenol als potentielle Maske für Nukleosidtriphosphat-Prodrugs
- Nora Constanze Fohrmann Computerbasierte und synthetische Strukturoptimierung von DHODH-Inhibitoren zum Einsatz gegen Bunyaviren
2016
- Patrick Dekiert: Synthese lipophiler Prodrugs von NAADP
- Nils Jeschik: On the way to lipophilic masked photocaged Adenosine triphosphate
- Alexander Laubach: Synthesis of fluorescent chemosensors for investigation of Adenosintriphosphate on cell surfaces
- Hiba Nasser: Synthetic and analytic studies towards prodrugs of the T-705-ribonucleotides