Research at the Institute of Pharmacy focuses on drug discovery, overlapping largely with the key priority areas of the Department of Chemistry: drug development for infectious diseases and material/nano chemistry . The Institute of Pharmacy provides a natural link between medical research and molecular sciences, bridging the gap between the Department of Chemistry and both medicine (UKE University Hospital) and biology as well as research centres outside the university such as the HPI and the Forschungszentrum Borstel.
Interests range from rational and computer assisted development (Lemcke group) to the development of new antibacterial surfaces (Maison group) via the synthesis of (marine) natural products (Schützenmeister group). Research of the medicinal chemistry teams is complemented by microbiology projects of the Heisig group working on the mechanisms of resistance found in microorganisms. It is round off by clinical pharmacy projects of the Wicha group exploring individual therapy concepts for special patient populations through pharmacometrics and therapeutic drug monitoring, particularly regarding anti-infectives. The Institute has a long standing close cooperation with the UKE Pharmacy.
Research at the Institute of Pharmacy addresses current topics of infection research: identification of new anti-infectives, resistance mechanisms, clinical hygiene and drug management. We have local cooperations with research groups of other institutes of the Department of Chemistry, the University Hospital, the Department of Biology and the HPI. Research at the Institute of Clinical Pharmacology and Toxicology (Oetjen group) deals with the pathomechanisms of cardiovascular diseases, focusing on the importance of nitric oxide metabolism, the development of cardiovascular diseases and the genesis of diabetes mellitus and its complications.
Material and Nano Chemistry
Research on functional materials is performed in the Leopold group. Projects in this area are related to drug formulation and tailored drug release by polymeric coatings. The Maison group works on tailored metals and plastics for implants and clinical hygiene. Research of both groups focuses on practical applications and extensive cooperation projects are carried out with industrial companies and other institutions such as HZG. We are furthermore interested in topics related to surfaces and nano particles (Leopold and Maison groups).