Prof. Dr. Claudia S. Leopold
Photo: Claudia S. Leopold
Research group leader
RG Leopold
Address
University of Hamburg
Department of Chemistry
Institute of Pharmacy
Research Group Leopold
Bundesstraße 45
20146 Hamburg
Office
Room: 302
Contact
Tel: +49 40 42838-3479
Fax: +49 40 42838-6519
Key aspects of activity
- Specialist Pharmacist for Pharmaceutical Technology
- Control of drug release through interactions
- between coating polymers
- Improvement of the water solubility of active ingredients by
- (Co-)amorphization
- Optimization of process flows during
- tableting through new design-based
- approaches
- Development of new imaging techniques for
- characterization of pellets and tablets
- Use of coprocessed excipients for tabletting
- of adhesive or abrasive active ingredients
Curriculum vitae
| 1981 - 1985 | Study of pharmacy at the Heinrich-Heine-University Düsseldorf |
| 1986 | Pharmacy internship (Ahorn Pharmacy, Langenfeld/Rhineland) |
| 14.01.1987 | Licensed pharmacist |
| 1987 - 1992 |
Scientific employee at the Institute for Pharmaceutical Technology of the Heinrich-Heine-University Düsseldorf Promotion with Prof. Dr. B.C. Lippold |
| 01.07.1992 |
Doctorate (Dr. rer. nat.) Topic: "Enhancer effects of lipophilic ointment bases on steady-state penetration of methyl nicotinate through the skin." |
|
08.1992 - 01.1994 |
Research stay with Dr. David R. Friend (Stanford Research Institute, Controlled Release and Biomedical Polymers Department, Menlo Park, USA) as a fellow of the German Research Foundation (DFG) |
|
02.1994 - 01.2000 |
Research Assistant at the Institute for Pharmaceutical Technology, Heinrich-Heine-University Düsseldorf, Germany |
| 17.01.1994 | Specialist pharmacist for pharmaceutical technology |
| 09.02.1994 | Authorization for continuing education in the field of pharmaceutical technology |
|
07.1995 - 10.1995 07.1998 - 10.1998 |
Forschungsaufenthalte bei Prof. Dr. Howard I. Maibach (School of Medicine, Department of Dermatology, University of California, San Francisco, USA) als Stipendiatin der Deutschen ForschungsgemeinschaftResearch stays with Prof. Dr. Howard I. Maibach (School of Medicine, Department of Dermatology, University of California, San Francisco, USA) as a fellow of the German Research Foundation (DFG) |
|
05.10.1997 |
Habilitation Award of the German Pharmaceutical Society (Division of Pharmaceutical Technology) |
|
7.12.1999 |
Habilitation at the Heinrich-Heine-University Düsseldorf. Topic: "Importance of formulation for drug availability using the example of colon targeting and cutaneous penetration". |
| 25.1.2000 | Award of the Venia legendi |
|
02.2000 - 09.2000 |
University lecturer at the Institute for Pharmaceutical Technology, Heinrich Heine University Düsseldorf |
|
10.2000 - 09.2005 |
University Professor (C3) at the Institute of Pharmacy -Pharmaceutical Technology-, University of Leipzig |
|
07.2002 - 09.2002 |
Research stay with Prof. Dr. Howard I. Maibach (School of Medicine, Department of Dermatology, University of California, San Francisco, USA) as a project of the German Research Foundation (DFG) |
| seit 10.2005 | University Professor (W 3), Head of the Department of Pharmaceutical Technology at the University of Hamburg |
|
11.2007 - 10.2011 |
Executive Director of the Institute of Pharmacy at the University of Hamburg |
|
08.2013 - 07.2016 |
Vice President for Research and Promotion of Young Academics at the University of Hamburg |
| 10.2016 - 03.2017 | Research Freesemester |
Congress contributions since 2005
| 2018 |
| Dülle M., Özcoban H., Leopold C.S. Investigation on the residence time distribution of a rotary tablet press with special focus on the feed frame system 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2018, Granada |
| Kalies A., Özcoban H., Leopold C.S. Instrumentation of a lower punch vibration equipment on a rotary tablet press for enhanced die filling 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2018, Granada |
| Dühlmeyer K.P., Özcoban H., Leopold C.S. A novel method for determination of the filling level in the feed frame of a rotary tablet press 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2018, Granada |
| Petry I., Löbmann K., Grohganz H., Rades T., Leopold C.S. In vivo co-amorphisation of APIs in the stomach – a proof of concept 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2018, Granada |
| Zier K.I., Schultze W., Leopold C.S. Addition of maltodextrin to Sennae fructus extracts during spray-drying, fluidized bed granulation, and freeze-drying 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2018, Granada |
| 2017 |
| Al-Karawi C., Kaiser T.M., Leopold C.S. A novel technique for characterization of sticking to tableting punch surfaces 31th Meeting of the American Association of Pharmaceutical Scientists (AAPS) 2017, November 12th-15th, San Diego, Kalifornien |
| Kalies A., Özcoban H., Leopold C.S. Application of pneumatic punch vibration for densification enhancement of pharmaceutical powders 31th Meeting of the American Association of Pharmaceutical Scientists (AAPS) 2017, November 12th-15th, San Diego, Kalifornien |
| Petry I., Löbmann K., Grohganz H., Rades T., Leopold C.S. The Influence of Arginine and Moisture on the Solid State Properties and Chemical Stabilityof Indomethacin 31th Meeting of the American Association of Pharmaceutical Scientists (AAPS) 2017, November 12th-15th, San Diego, Kalifornien |
| Petry I., Löbmann K., Grohganz H., Rades T., Leopold C.S. How arginine in combination with moisture influences the solid state and chemical stability of indomethacin 11th Annual Meeting of the Pharmaceutical Solid State Research Cluster (PSSRC) 2017, June 28th-30th, Graz |
| 2016 |
| Petry I., Löbmann K., Grohganz H., Rades T., Leopold C.S. A new method for visualization of sticking material to tablet punch surfaces 10th Annual Meeting of the Pharmaceutical Solid State Research Cluster (PSSRC) 2016, July 6th – 8th, Copenhagen |
| Al-Karawi C., Skiba M., Sakmann A., Kaiser T.M., Leopold C.S. Characterization of film-coated tablets consisting of either co-amorphous or crystalline indomethacin-arginine 30th Meeting of the American Association of Pharmaceutical Scientists 2016, 13.-17. November 2016, Denver, Colorado |
| Petry I., Löbmann K., Grohganz H., Rades T., Leopold C.S. Coated crystalline indomethacin-arginine tablets undergo /in situ/ amorphisation when stored at high humidity 30th Meeting of the American Association of Pharmaceutical Scientists 2016, 13.-17. November 2016, Denver, Colorado |
| 2015 |
| Novikova A., Sakmann A., Carstensen J.M., Rades T., Leopold C.S. UV imaging of MUPS tablets: pellet content and distribution analysis 7th pan-European QbD & PAT Science Conference 2015, Graz |
| Klukkert M., Wu J.X., Rantanen J., Carstensen J.M., Rades T. , Leopold C.S. Multispectral UV imaging for fast and non-destructive quality control of tablets. 7th pan-European QbD & PAT Science Conference 2015, Graz |
| Novikova A., Sakmann A., Carstensen J.M., Rades T., Leopold C.S. Pellet Distribution Analysis by UV Imaging and HPLC: A comparative Study 42nd Annual Meeting & Exposition of the Controlled Release Society 2015, Edinburgh |
| Beyer A., Löbmann K., Grohganz H., Rades T., Leopold C.S. Influence of the blend ratio on the physical stability of co-amorphous naproxen-indomethacin 9th Pharmaceutical Solid-State Research Cluster Symposium 2015, Ghent |
| Novikova A.,Carstensen J.M., Zeitler A., Rades T., Leopold C.S. UV imaging for determination of the coating layer thickness of coated tablets 9th Pharmaceutical Solid-State Research Cluster Symposium 2015, Ghent |
| Al-Karawi C., Sakmann A., Leopold C.S. Investigation on the Adhesion Tendency of Ibuprofen and Ibuprofen Sodium Dihydrate on Coated Tablet Tooling 29th Meeting of the American Association of Pharmaceutical Scientists 2015, Orlando |
| Beyer A., Löbmann K., Grohganz H., Rades T., Leopold C.S. Multivariate quantification of the solid-state phase composition of co-amorphous naproxen-indomethacin in dependence of the storage time 29th Meeting of the American Association of Pharmaceutical Scientists 2015, Orlando |
| Novikova A.,Carstensen J.M., Rades T., Leopold C.S. Determination of the coating layer thickness of coated tablets by UV imaging 29th Meeting of the American Association of Pharmaceutical Scientists 2015, Orlando |
| Al-Karawi C., Schoeler M., Sakmann A., Leopold C.S. Influence of tooling roughness and ibuprofen particle size on tablet sticking Symposium on Pharmaceutical Engineering Research 2015, Braunschweig, Germany |
| 2014 |
| Klukkert M., Wu J.X., Carstensen J.M., Rades T., Leopold C.S. High-throughput quality control of critical physical tablet attributes by UV multispectral imaging 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2014, Lisbon |
| Al-Karawi C., Sakmann A., Leopold C.S. Influence of chromium nitride punch tip coating and a co-processed self-lubricating excipient on the sticking of ibuprofen tablets 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2014, Lisbon |
| Beyer A., Löbmann K., Grohganz H., Rades T., Leopold C.S. Aging and Molecular Rearrangement in co-amorphous indomethacin and naproxen 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2014, Lisbon |
| Novikova A., Sakmann A., Rades T., Carstensen J.M., Leopold C.S. UV imaging of MUPS tablets: Surface analysis of the pellet distribution 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2014, Lisbon |
| Wulff R., Leopold C.S. Drug release from mini tablets coated with Eudragit® RL and Eudragit® L55 in biorelevant dissolution media 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2014, Lisbon |
| Klukkert M., Sakmann, A., Rehder, S., Carstensen, J.M., Rades, T., Leopold, C.S. Multispectral UV imaging for high-speed quality control in the manufacturing process of tablets 6th International Congress on Pharmaceutical Engineering 2014, Graz |
| Klukkert M., Wu J.X., Carstensen J.M., Rades T., Leopold C.S. Multispectral UV Imaging for quality control of tablets 16th International Workshop on Physical Characterization of Pharmaceutical Solids 2014, Prag |
| Biller J., Klukkert M., Morschheuser L., Leopold C.S. Trusch M., Rohn S. Massenspektrometrische Charakterisierung von Enzym-Lactose-Derivaten 47. Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie 2014, Frankfurt |
| Klukkert M., Wu J.X., Carstensen J.M., Rades T., Leopold C.S. High-speed determination of the radial tensile strength of tablets by multispectral UV imaging 2014 AAPS Annual Meeting and Exposition, San Diego |
| Klukkert M., Wu J.X., Carstensen J.M., Rades T., Leopold C.S. Multispectral imaging for determination of an interaction between protein API and excipient during tableting and storage - A multifactorial approach 2014 AAPS Annual Meeting and Exposition, San Diego |
| Novikova A., Carstensen J.M., Rades T., Leopold C.S. UV imaging of MUPS tablets: A stability study 2014 AAPS Annual Meeting and Exposition, San Diego |
| Beyer A., Löbmann K., Grohganz H., Rades T., Leopold C.S. Preparation of co-amorphous naproxen-indomethacin by cooling the melt using different cooling methods 2014 AAPS Annual Meeting and Exposition, San Diego |
| Beyer A., Radi L., Löbmann K., Grohganz H., Rades T., Leopold C.S. Preparation and physical stability of spray-dried co-amorphous naproxen-indomethacin 8th Pharmaceutical Solid-State Research Cluster Symposium 2014, Ljubljana |
| 2013 |
| Rehder S., Rades T., Leopold C.S. Recrystallization of amorphous glibenclamide in tablets – a multifactorial approach 40th Annual Meeting & Exposition of the Controlled Release Society 2013, Honolulu |
| Wulff R., Leopold C.S. Investigation of the dissolution behavior of Eudragit® RL/L-55 blends using a response surface methodology 40th Annual Meeting & Exposition of the Controlled Release Society 2013, Honolulu |
| Klukkert M., Sakmann A., Rades T., Leopold C.S. Investigation of the influence of tableting on the conformational and thermal stability of a model protein 40th Annual Meeting & Exposition of the Controlled Release Society 2013, Honolulu |
| Novikova A., Leopold C.S. Design of experiments approach for the development of coated pellets for MUPS tablets 40th Annual Meeting & Exposition of the Controlled Release Society 2013, Honolulu |
| Klukkert M., Wu J.X., Carstensen J.M., Rades T., Leopold C.S. Fast determination of API surface distribution in multicomponent enzyme tablet formulations by UV imaging 2013 AAPS Annual Meeting and Exposition, San Antonio |
| Beyer A., Löbmann K., Grohganz H., Rades T., Leopold C.S. Influence of tableting and storage on the physical stability of a coamorphous system 2013 AAPS Annual Meeting and Exposition, San Antonio |
| Wulff R., Leopold C.S. How to achieve zero order release kinetics of acidic drugs by coating with blends of Eudragit® RL/L55 2013 AAPS Annual Meeting and Exposition, San Antonio |
| 2012 |
| Michaelis M., Leopold C.S. The Probe Tack Test: A Design of Experiments Approach 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2012, Istanbul |
| Rehder S., Wu J. X., Laackmann J., Rantanen J., Moritz H.-U., Rades T., Leopold C. S. Real-time monitoring of solid-state phase transformation of acoustically levitated particles using near infrared spectroscopy 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2012, Istanbul |
| Wulff R., Leopold C.S. Infrared study on blends of Eudragit® RL and Eudragit® L-55 using Principal Component Analysis 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2012, Istanbul |
| Saniocki I., Sakmann A., Leopold C.S. Impact of punch tip coating on the anti-adherent performance of the lubricant magnesium stearate during direct compression of various excipients 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2012, Istanbul |
| Rehder S., Rades T., Leopold C.S. Technological characterization of cocrystal granules formed by high-shear granulation 2012 AAPS Annual Meeting and Exposition, Chicago |
| Wulff R., Leopold C.S. Comparison of pellets coated with organic solutions and aqueous dispersions of Eudragit® RL/L-55 blends: Investigation of drug release 2012 AAPS Annual Meeting and Exposition, Chicago |
| 2011 |
| Rehder S., Klukkert M., Strachan C.J., Sakmann A., Rades T., Leopold C.S. Investigation of Piracetam Cocrystals Formation During Different Grinding Procedures by Raman Spectroscopy 38th Annual Meeting & Exposition of the Controlled Release Society 2011, National Harbor |
| Saniocki I., Sakmann A., Leopold C.S. Effect of punch tip coating and geometry on the sticking tendency of an ibuprofen tablet formulation 38th Annual Meeting & Exposition of the Controlled Release Society 2011, National Harbor |
| Michaelis M., Leopold C.S. Influence of ibuprofen content on the adhesion properties and rheological behavior of an acrylic pressure sensitive adhesive Skin Forum 12th Annual Meeting 2011, Frankfurt |
| Michaelis M., Leopold C.S. Rheological and adhesion properties of a crosslinked acrylic pressure sensitive adhesive used for transdermal patches containing ibuprofen GDCh Forum 2011, Bremen |
| Rehder S., Kniese M., Sakmann A., Rades T., Leopold C.S. Formation of piracetam-tartaric acid cocrystals during high shear granulation DPhG Jahrestagung 2011, Innsbruck |
| Saniocki I., Sakmann A., Leopold C.S. Impact of the lubricant type on compaction and tablet properties of sorbitol formulations DPhG Jahrestagung 2011, Innsbruck |
| Klukkert M., Rehder S., Loebmann K., Strachan C.J., Rades T., Leopold C.S. Investigation of cocrystal formation during storage using Raman spectroscopy and chemometrics 2011 AAPS Annual Meeting and Exposition, Washington DC |
| Saniocki I., Klukkert M., Sakmann A., Leopold C.S. Compaction of tablet formulations based on Ludipress® containing high-dose poorly compressible and pressure-sensitive drugs 2011 AAPS Annual Meeting and Exposition, Washington DC |
| Rehder S., Laackmann J., Rantanen J., Moritz H.-U., Rades T., Leopold C. S. Emulation of spray-freeze drying in a fluidized bed by acoustic leviation and Raman spectroscopy 2011 AAPS Annual Meeting and Exposition, Washington DC |
| 2010 |
| Conradi R., Leopold C.S. The influence of coating composition on the anion-controlled pulsatile drug release of Eudragit® RS 30D-coated theophylline pellets 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2010, Malta |
| Saniocki I., Sakmann A., Leopold C.S. Compactibility and sticking properties of ibuprofen containing Microcelac® 100 tablets 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2010, Malta |
| Farag Y., Leopold C.S. Modification of drug release from shellac coated pellets by ionic interactions 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2010, Malta |
| Hentzschel C.M., Sakmann A., Leopold C.S. Suitability of various tableting excipients as carriers for liquisolid systems 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2010, Malta |
| Alnaief M., Smirnova I., Antonyuk S., Heinrich S., Hentzschel C.M., Conradi R., Leopold C.S. Aerogel based solid dosage forms for targeted drug delivery 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2010, Malta |
| Gasch J., Leopold C.S., Knoth H. Drug retention by inline filters 15th Congress of the European Association of Hospital Pharmacists 2010, Nizza |
| Farag Y., Leopold C.S. Sustained drug release from shellac-coated pellets with different subcoats 37th Annual Meeting & Exposition of the Controlled Release Society 2010, Portland |
| Hentzschel C.M., Alnaief M., Smirnova I., Sakmann A., Leopold C.S. Hydrophilic silica aerogels and liquisolid systems - Two drug delivery systems to enhance dissolution rates of poorly soluble drugs 37th Annual Meeting & Exposition of the Controlled Release Society 2010, Portland |
| Rehder S., Sakmann A., Rades T., Leopold C.S. Stability of triturations containing amorphous ketoprofen during tableting 37th Annual Meeting & Exposition of the Controlled Release Society 2010, Portland |
| Saniocki I., Sakmann A., Leopold C.S. Characterization of the sticking tendency during tablet manufacture - take-off force measurements and quantification of material adhering to the punch surface 37th Annual Meeting & Exposition of the Controlled Release Society 2010, Portland |
| Rehder S., Sakmann A., Rades T., Leopold C.S. Characterization of the sublimate of amorphous glibenclamide formed during dry heating 2010 AAPS Annual Meeting and Exposition, New Orleans |
| Saniocki I., Sakmann A., Leopold C.S. Investigation of Sticking during Tablet Manufacture – Compaction of binary mixtures of ibuprofen and Ludipress® AAPS Annual Meeting & Exposition 2010, New Orleans |
| Michler V.A., Leopold C.S. Compounding of suspension-type ointments with electric mixing systems and three roll mills – a comparative study 2010 AAPS Annual Meeting and Exposition, New Orleans |
| Michaelis M., Leopold C.S. Influence of ibuprofen content on adhesion properties of an acrylic pressure sensitive adhesive 2010 AAPS Annual Meeting and Exposition, New Orleans |
| Michler V.A., Leopold C.S. Compounding of suspension-type ointments – a comparative study DPhG Jahrestagung 2010, Braunschweig |
| Hentzschel C.M., Sakmann A., Leopold C.S. Enhancement of Griseofulvin Release from Liquisolid Compacts and Optimization thereof DPhG Jahrestagung 2010, Braunschweig |
| Saniocki I., Sakmann A., Leopold C.S. Quantification of Sticking to the Punch Surfaces during Tablet Manufacture DPhG Jahrestagung 2010, Braunschweig |
| Michaelis M., Leopold C.S. Influence of ibuprofen content on the rheological and thermal behavior of an acrylic pressure sensitive adhesive DPhG Jahrestagung 2010, Braunschweig |
| 2009 |
| Conradi R., Leopold C.S The influence of anionic drugs on the thermal properties of free Eudragit® RS and RL films 6th International Controlled Release EUDRAGIT® Workshop 2009, Darmstadt |
| Conradi R., Leopold C.S. Effect of drugs on the swelling behavior of free Eudragit® RS and RL films 36th Annual Meeting & Exposition of the Controlled Release Society 2009, Kopenhagen |
| Farag Y., Leopold C.S. Influence of the coating temperature on drug release of shellac coated pellets 36th Annual Meeting & Exposition of the Controlled Release Society 2009, Kopenhagen |
| Hentzschel C.M., Sakmann A., Leopold C.S. Influence of the magnesium stearate concentration on the tabletability of various excipients 36th Annual Meeting & Exposition of the Controlled Release Society 2009, Kopenhagen |
| Farag Y., Leopold C.S. Comparison of physicochemical and coating properties of different shellac types 2009 AAPS Annual Meeting and Exposition, Los Angeles |
| Hentzschel C.M., Sakmann A., Leopold C.S. Comparison of physical and tableting properties of traditional and novel excipients 2009 AAPS Annual Meeting and Exposition, Los Angeles |
| Conradi R., Leopold C.S. Anion-controlled pulsatile drug release from Eudragit® RS 30 D-coated theophylline pellets DPhG Jahrestagung 2009, Jena |
| Farag Y., Leopold C.S. Simulation of the aging process of shellac by thermal treatment DPhG Jahrestagung 2009, Jena |
| Hentzschel C.M., Sakmann A., Alnaief M., Smirnova I., Leopold C.S. Tableting properties of silica aerogel and various silicates DPhG Jahrestagung 2009, Jena |
| 2008 |
| Conradi R., Leopold C.S. The influence of anionic drugs on the thermal properties of free Eudragit® RS and RL films 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2008, Barcelona |
| Hanusa E., Leopold C.S. Pressure change technology as a gentle cold sterilisation procedure for thermosensitive drug solutions 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2008, Barcelona |
| Farag Y., Leopold C.S. New insights into the properties of shellac 35th Annual Meeting & Exposition of the Controlled Release Society 2008, New York City |
| Hanusa E., Leopold C.S. Stability of aqueous human insulin solutions after pressure change 35th Annual Meeting & Exposition of the Controlled Release Society 2008, New York City |
| Farag Y., Leopold C.S. Investigation of the dissolution properties of shellac by the intrinsic dissolution method DPhG Jahrestagung 2008, Bonn |
| Hentzschel C.M., Sakmann A., Leopold C.S. Influence of liquid drug content on the flow properties of liquisolid powder blends DPhG Jahrestagung 2008, Bonn |
| Gasch J., Leopold C.S., Oertel R., Kirch W., Knoth H. Untersuchung der Verunreinigung in Infusionsfiltern durch N,N-Dimethylacrylamid ADKA Jahreskongress 2008, Lübeck |
| Gasch J., Knoth H., Leopold C.S. N,N-Dimethylacrylamide in infusion filters DPhG Jahrestagung 2008, Bonn |
| Hentzschel C.M., Sakmann A., Leopold C.S. Flowability of liquisolid powder blends 2008 AAPS Annual Meeting and Exposition, Atlanta |
| Hentzschel C.M., Saniocki I., Sakmann A., Leopold C.S. Particle size, surface area and flowability of novel tableting excipients Porotec Workshop 2008, Bad Soden |
| 2007 |
| Hanusa E., Leopold C.S. An optimized Pin Prick Test for the pharmacodynamic quantification of the cutaneous penetration of local anaesthetics: A pilot study 34th Annual Meeting & Exposition of the Controlled Release Society 2007, Long Beach |
| Conradi R., Leopold C.S. The influence of ionic drugs on the thermal properties of free Eudragit® RS and RL films. DPhG Jahrestagung 2007, Erlangen |
| 2006 |
| Hanusa E., Döge U., Wecks M., Leopold C.S. Pressure change technology as novel sterilisation method? 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2006, Genf |
| Wiedersberg S., Leopold C.S., Guy R.H. Dermatopharmacokinetics of betamethasone-17-valerate: Influence of the drug removal procedure 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology 2006, Genf |
| Kaiser S., Hagels H., Leopold C.S. Does moisture influence the stability of ingredients in St. John's Wort extracts? DPhG Jahrestagung 2006, Marburg |
| Wiedersberg S., Leopold C.S., Guy R.H. Dermatopharmacokinetics of betamethasone-17-valerate: Influence of the gelling agent APGI 2nd Symposium on Skin and Formulation 2006, Versailles |
| Wiedersberg S., Leopold C.S., Guy R.H. Dermatopharmacokinetics of betamethasone-17-valerate: Influence of drug thermodynamic activity Skin Forum 2006, Sheffield |
| Dutz S., Andrä W., Leopold C.S., Bellemann M.E. Release profiles of magnetically triggered capsules for remote controlled drug delivery World Congress of Medical Physics and Biomedical Engineering 2006, Seoul |
| Ploen J., Andersch J., Heschel M., Leopold C.S. An extended release pellet formulation of propiverine hydrochloride prepared by fluid bed coating: Differences in drug release between the free base and the salt as active ingredient 2006 AAPS Annual Meeting and Exposition, San Antonio |
| 2005 |
| Leopold C.S., Maibach H.I. Percutaneous penetration of local anesthetics: Pharmacodynamic measurements. Joint Meeting SCUR & ISP 2005, Hamburg |
| Ploen J., Andersch J., Heschel M., Leopold C.S. An extended release pellet formulation of propiverine hydrochloride prepared by fluid bed coating: Effect of citric acid and microcrystalline cellulose as starter cores. 32nd Annual Meeting & Exposition of the Controlled Release Society 2005, Miami Beach |
| Dutz S., Andrä W., Leopold C.S., Bellemann M.E. Remote controlled drug delivery to the gastrointestinal tract: investigation of release profiles BMT 2005, Nürnberg |
| Hanusa E., Leopold C.S. Pressure change technology as novel sterilisation method? DPhG Jahrestagung 2005, Mainz |
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