Completed Diploma and Master's Theses
2025
- Dennis Nahler: Synthesis of novel hydroxamic acid-based LpxC inhibitors
2024
- Julian Bartenbach: Synthesis of proline based LpxC inhibitors
- Timm Krüger: Synthesis of LpxA Inhibitors
- Arianna Gorgoni: Synthesis and biological evaluation of new amino acid-based LpxC Inhibitors
2023
- Elisa Venanzi: Synthesis and biological evaluation of a galactose-derived C-furanosidic inhibitor of the bacterial deacetylase LpxC
- Frederick Wichter: Synthese und Struktur-Wirkungs-Beziehungen von Triazol-basierten LpxC-Inhibitoren
- Fabian Lüttchens: Chiral pool synthesis of acyclic LpxC inhibitors
- Niyusha Goudarzi-Bozargomehri: Synthesis and Structure-Activity Relationships of Benzyloxyacetic acid-Derivatives as LpxC-Inhibitors
2022
- Jan von Rönn: Synthesis of new LpxC inhibitors on the basis of amino acids
- Vanessa Di Muzio: Synthesis and biological evaluation of isoserine-based hydroxamic acids as LpxC inhibitors
- Anna Falconi: Synthesis of α-branched esters as intermediates for the preparation of LpxC inhibitors
2020
- Stefan Wimmer: Synthesis of Novel Tetrose Based LpxC Inhibitors
- Alice Casadidio: Synthesis and biological evaluation of acylamidomethyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors
- Rúben Manuel Figueira de Abreu: Syntheses and Structure-Activity Relationships of Arabinose-Based LpxC-Inhibitors
- Raquel Lascorz Massanet: Synthesis and Biological Evaluation of Arabinitol-Derived LpxC Inhibitors
- Patrick Myslinski: Synthesis and structure-activity relationships of proline-based inhibitors of Zn2+-dependent enzymes
2019
- Arianna Colò: Synthesis and Biological Evaluation of Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC
- Laura Denni: Synthesis and Biological Evaluation of Arabinitol-Derived LpxC Inhibitors
- Manlio Caldara: Synthesis and Biological Evaluation of Benzyloxyacetohydroxamic Acid-derived LpxC Inhibitors
2018
- Alessia Latorrata: Proline-based hydroxamic acids as inhibitors of Zn2+-dependent enzymes
Giuseppe Casamassima: Synthesis and structure-activity relationships of benzyloxyacetic acid-derived LpxC-inhibitors - Katharina Hoff: Inhibition of lipid A biosynthesis: LpxD’s cloning, a novel LpxC-enzyme assay’s development and biological evaluation of LpxC-inhibitors
- Max Schwenk: Synthesis and structure–activity relations of influenza nucleoprotein inhibitors
2017
- Timo Allen: Synthese und Struktur-Wirkungsbeziehung von C-glycosidischen LpxC-Inhibitoren
Westfälische Wilhelms-Universität Münster
2017
- Martin Grever: Tetrose-basierte LpxC-Inhibitoren: Synthese und Struktur-Wirkungsbeziehungen
2016
- Denise Ilari: Synthesis and Biological Evaluation of Isoserine-Based LpxC Inhibitors
- Benedikt Martin: Synthese und Struktur-Wirkungsbeziehungen von Erythrose-basierten LpxC-Inhibitoren
- Omar Kharwb: Synthesis and biological evaluation of penturonic acid derivatives as LpxC inhibitors
- Maxim Pfafenrot: Glycerinsäure-Derivate als potentielle LpxC-Inhibitoren: Synthese und Struktur-Wirkungsbeziehungen
2015
- Matthias Hoffmann: Synthese und biologische Testung von Gylcerinsäure-Derivaten als LpxC-Inhibitoren
- Sebastian Mielniczuk: Synthese und biologische Testung von Triazol-Derivaten als LpxC-Inhibitoren
2014
- Tullio Torregrossa: Asymmetric synthesis of glyceric acid derived LpxC inhibitors using lipases as chiral catalysts
- Maria Teresa Iorio: Synthesis of amide- and triazole-based phenyl ethylene glycol-derivatives as LpxC inhibitors
- Valeria Gabrielli: Synthesis and biological evaluation of mono- and dialkylated C-furanosides as inhibitors of the deacetylase LpxC
- Ilaria Bagozzi: Untersuchung des Metabolismus von LpxC-Inhibitoren mit Benzyloxyessigsäure-Struktur
2013
- Oriana Agoglitta: Synthesis and Biological Evaluation of Benzyloxyacetic Acid Derivatives as LpxC Inhibitors
- Giovanni Tangherlini: Chiral Pool Synthesis of Glyceric Acid Ether Derivatives as LpxC Inhibitors
2012
- Marina Szermerski: Bioisostere LpxC-Inhibitoren: Enantioselektive Synthese und Struktur-Wirkungs-Beziehung von Benzyloxyessigsäure-Derivaten
- Elisa Ravarino: Stereocontrolled Synthesis of 1,4-Disubstituted C-Furanosides as Key Intermediates in the Discovery of LpxC Inhibitors
2011
- Carla Pulina: Synthesis of C-Furanosides as LpxC Inhibitors
2010
- Alberto Oddo: Synthesis, Characterisation and Evaluation of Novel C-Arylfuranosides as LpxC-Inhibitors