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Department of Chemistry
Departmentof Chemistry
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Photo: Thomas Lemcke

Teaching

Lectures

  • "Pharmaceutical/Medicinal Chemistry: Fundamentals of Quantitative Analytics" (1 credh). This lecture is given in conjunction with the seminar accompanying the lab-course  on quantitative analytics. For further details, please see the information for the 2nd course semester.

  • "Pharmaceutical/Medicinal Chemistry:  Pharmacopoeial Analytics" (1 credh). This lecture is given in conjunction with the seminar accompanying the lab-course on pharmacopoeial analytics For further information, please see the information for the 5th course semester.

  • "Introduction to Medicinal Chemistry" (2 credh). This lecture pertains to both the programme of the pharmacy course (5th course semester) and to module CHE356 of the chemistry and molecular lifescience courses and is also part of module MBI16-5 of the bioinformatics master course.

  • "Fundamentals in Biochemistry" (1 credh)

  • "Biochemistry and Molecular Biology" (3 credh)

Seminars

  • Seminar accompanying the lab-course on "Quantitative Determination of Drug Substances, Excipients and Xenobiotics" (2 credh). This seminar will be given in conjunction with lecture "Fundamentals of Quantitative Analytics". For further details, please see information for the 2nd course semester.
  • Seminar accompanying the lab-course "Analytics of Drug Substances with Special Consideration  of Pharmacopoeias" (2 credh). This seminar will be given in conjunction with lecture "Pharmacopoeial Analytics". For further information, please see the information for the 5th course semester.

Lab-courses

  • "Quantitative Determination of Drug Substances, Excipients and Xenobiotics (including Pharmacopoeial Methods) (8 credh)

  • "Analysis of Drug Substances with Special Consideration of the Pharmacopoeias"  (6 credh)

  • Analytics of Drugs, Drugmonitorin, Toxicological and Environmen Related Studies (10 credh)

Lap Options

For lab options, we offer research projects related to molecular modelling and to medicinal chemistry assisted by computer methods. These projects will be worked on in small groups during the holidays. In the past years, the following projects have been carried out:

  • C. Petersen: Docking of a Series of Paullones into the ATP-Binding Site of CDK1 and GSK-3β
  • S. Kruggel: Docking of Paullones into the Active Site of CDK5 using FlexX and FlexS, Evaluation of a corresponding CoMSIA Analysis
  • J.H. Löhr and T. Wagner: Characterization of the ATP Binding Pockets of Human GSK-3β with the Help of Molecular Interaction Fields (MIFás).
  • S. Vogel: Building of a Homology Model of Plasmodium falciparum Glycogen Synthase Kinase-3
  • S. Kienapfel and L. Petersen: Studies on the Binding Mode of JM111a and its Derivatives in the ATP Binding Pocket of SRC Tyrosine Kinase
  • M. Giertz and Moritz Münsterberg: Evaluation of the Docking Programme  FRED Comparative Crossdocking of various GSK-GSK-3β Inhibitors.
  • S. Kellermann and J. Holstein:  Comparative study of ATP Binding Pockets of Available X-Ray structures of the Protein Kinases BRAF andMEK (research project in the chemistry master course)