Research

These are some projects of the group:

• Low resolution force fields for protein structure prediction / protein threading
• Abuse of force fields - turning them into substitution matrices, building ones for special problems
• Scoring functions and methodology for optimising protein sequences
• Model systems on lattices for problems like free energy estimation and sequence optimisation
• Methods for protein sequence to structure alignment

 

KEY PUBLICATIONS

Repurposing tRNAs for nonsense suppression.
Albers S, Beckert B, Matthies MC, Mandava CS, Schuster R, Seuring C, Riedner M, Sanyal S, Torda AE, Wilson DN, Ignatova Z. Nat Commun. 2021 Jun 22;12(1):3850.
https://pubmed.ncbi.nlm.nih.gov/34158503/

Dynamics in Sequence Space for RNA Secondary Structure Design.
Matthies MC, Bienert S, Torda AE. J Chem Theory Comput. 2012 Oct 9;8(10):3663-70.
https://pubmed.ncbi.nlm.nih.gov/26593011/

Fast alignment and comparison of RNA structures.
Wiegels T, Bienert S, Torda AE. Bioinformatics. 2013 Mar 1;29(5):588-96.
https://pubmed.ncbi.nlm.nih.gov/23314325/