Fachbereich Chemie
Publikationssuche
2024 | |
473 |
Controlling the size, shape, and stability of SeNPs by bromelain: Improved antioxidant, anti-bacterial and anti-cancer activities Surriya Bibi, Aisha Munawar, Muhammad Waqas Ishaq, Fakhar Zaman, Muhammad Abid, Ali Rafi, Ahsan Saeed, Ahmad Akrem, Robin Schubert, Usman Aftab, Syed Abid Ali, Christian Betzel , Irfan Ullah Khan Journal of Molecular Structure 1295, 136633 (11 pp) (2024) |
2023 | |
472 |
CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family Laritza Rojas, Aymara Cabrera-Muñoz, Luis A. Espinosa, Sergi Montané, Luis Alvarez-Lajonchere, Jesús D. Mojarena, Galina Moya, Julia Lorenzo, Luis J. González, Christian Betzel , Maday Alonso-del-Rivero Antigua Biochimie 213, 41-53 (2023) |
471 |
Calpeptin
is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections Patrick Y. A. Reinke, Edmarcia Elisa de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karnicar, Aleksandra Usenik, Nataša Lindic, Andreja Sekirnik, Viviane Fongaro Botosso, Gláucia Maria Machado Santelli, Josana Kapronezai, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Lizdany Flórez-Álvarez, Danielle Bruna Leal de Oliveira, Edison Luiz Durigon, Paula Roberta Giaretta, Marcos Bryan Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck , Russell Cox, Henry N. Chapman , Christian Betzel , Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa L. Latham, Ana Marcia de Sá Guimarães, Dusan Turk, Carsten Wrenger, Alke Meents Communications Biology 6, 1058 (2023) |
470 |
Weiterer Schritt zur Bekämpfung von Alzheimer CU - Chemie UniHamburg - Die Mitarbeiterzeitung (32) 20-21 (2023) (Auszug aus Pressemitteilung Universität Hamburg) (Thema: Christian Betzel ) |
469 |
Structure and dynamics of the penicillin-binding protein 3 from Staphylococcus epidermidis native and in complex with cefotaxime and vaborbactam Martin Schwinzer, Hévila Brognaro, Holger Rohde , Christian Betzel International Journal of Applied Biology and Pharmaceutical Technology 14, 60-75 (2023) |
468 |
Initiation and modulation of Tau protein phase separation by the drug suramin Prabhu Rajaiah Prince, Janine Hochmair, Hévila Brognaro, Susanna Gevorgyan, Maximilian Franck, Robin Schubert, Kristina Lorenzen, Selin Yazici, Eckhard Mandelkow, Susanne Wegmann, Christian Betzel Scientific Reports 13, 3963 (13 pp) (2023) |
467 |
Formation kinetics and physicochemical properties of mesoscopic Alpha-Synuclein assemblies modulated by sodium chloride and a distinct pulsed electric field Mengying Wang, Roland Thuenauer, Robin Schubert, Susanna Gevorgyan, Kristina Lorenzen, Hévila Brognaro, Christian Betzel Soft Matter 19, 1363-1372 (2023) |
466 |
Kinetics of protein phase separation modulated by pulsed electric fields and the role of mesoscopic clusters in crystallization and fibrillation Mengying Wang -/- Betreuer: Christian Betzel Dissertation, Hamburg (2023) |
465 |
Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro Janine Hochmair, Christian Exner, Christian Betzel , Eckhard Mandelkow, Susanne Wegmann Methods in Molecular Biology 2551 (Protein Aggregation) 225-243 (2023) |
2022 | |
464 |
Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development A. Moustafa, M. Perbandt , E. Liebau, C. Betzel , S. Falke Acta Crystallographica, Section F: Structural Biology Communications 78, 232-240 (2022) |
463 |
Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease V. Srinivasan, H. Brognaro, P. R. Prabhu, E. E. de Souza, S. Günther, P. Y. A. Reinke, T. J. Lane, H. Ginn, H. Han, W. Ewert, J. Sprenger, F. H. M. Koua, S. Falke, N. Werner, H. Andaleeb, N. Ullah, B. A. França, M. Wang, A. L. C. Barra, M. Perbandt , M. Schwinzer, C. Schmidt, L. Brings, K. Lorenzen, R. Schubert, R. R. G. Machado, E. D. Candido, D. B. L. Oliveira, E. L. Durigon, S. Niebling, A. S. Garcia, O. Yefanov, J. Lieske, L. Gelisio, M. Domaracky, P. Middendorf, M. Groessler, F. Trost, M. Galchenkova, A. R. Mashhour, S. Saouane, J. Hakanpää, M. Wolf, M. M. Garcia-Alai , D. Turk, A. R. Pearson , H. N. Chapman , W. Hinrichs, C. Wrenger, A. Meents , C. Betzel Communications Biology 5, 805 (12 pp) (2022) |
462 |
Exploring Nucleation Pathways in Distinct Physicochemical Environments Unveiling Novel Options to Modulate and Optimize Protein Crystallization M. Wang, A. L. C. Barra, H. Brognaro, C. Betzel Crystals 12, 437 (22 pp) (2022) |
461 |
Comparative Study to Characterise the Pharmaceutical Potential of Synthesised Snake Venom Bradykinin-Potentiating Peptides In Vivo A. Munawar, F. Zaman, M. W. Ishaq, K. A. Hassan, S. Masood, Z. Ali, K. A. Majeed, A. Akrem, S. A. Ali, C. Betzel Current Medicinal Chemistry 29, 6422-6432 (2022) |
460 |
Comprehensive Structural and Functional Characterization of a Seed γ-thionin as a Potent Bioactive Molecule Against Fungal Pathogens and Insect Pests B. Khaliq, M. Abdalla, S. Mehmood, A. Saeed, A. Munawar, M. Q. Saeed, Q. Saeed, M. Ibrahim, Z. Ali, S. Hussain, W. A. Eltayb, C. Betzel , A. Akrem Current Medicinal Chemistry 29, 6446-6462 (2022) |
459 |
Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates J. Hochmair, C. Exner, M. Franck, A. Dominguez-Baquero, L. Diez, H. Brognaro, M. L. Kraushar, T. Mielke, H. Radbruch, S. Kaniyappan, S. Falke, E. Mandelkow, C. Betzel , S. Wegmann EMBO Journal 41, e108882 (28 pp) (2022) |
458 |
Hydrazones and thiosemicarbazones targeting protein-protein-interactions of SARS-CoV-2 papain-like protease W. Ewert, S. Günther, F. Miglioli, S. Falke, P. Y. A. Reinke, S. Niebling, C. Günther, H. Han, V. Srinivasan, H. Brognaro, J. Lieske, K. Lorenzen, M. M. Garcia-Alai , C. Betzel , M. Carcelli, W. Hinrichs, D. Rogolino, A. Meents Frontiers in Chemistry 10, 832431 (2022) |
457 |
Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive K. A. Zielinski, A. Prester, H. Andaleeb, S. Bui, O. Yefanov, L. Catapano, A. Henkel, M. O. Wiedorn, O. Lorbeer, E. Crosas, J. Meyer, V. Mariani, M. Domaracky, T. A. White, H. Fleckenstein, I. Sarrou, N. Werner, C. Betzel , H. Rohde , M. Aepfelbacher , H. N. Chapman , M. Perbandt , R. A. Steiner, D. Oberthür IUCrJ 9, 778-791 (2022) |
456 |
Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD A. Ostendorp, S. Ostendorp, Y. Zhou, Z. Chaudron, L. Wolffram, K. Rombi, L. von Pein, S. Falke, C. M. Jeffries, D. I. Svergun, C. Betzel , R. J. Morris, F. Kragler, J. Kehr Journal of Biological Chemistry 198, 102631 (14 pp) (2022) |
455 |
Tracing transport of protein aggregates in microgravity versus unit gravity crystallization A. Martirosyan, S. Falke, D. McCombs, M. Cox, C. D. Radka, J. Knop, C. Betzel , L. J. DeLucas npj Microgravity 8, 4 (12 pp) (2022) |
454 |
Structure and activity of the DHNA Coenzyme-A Thioesterase from Staphylococcus aureus providing insights for innovative drug development A. Melro Murad, H. Brognaro, S. Falke, J. Lindner, M. Perbandt , C. Mudogo, R. Schubert, C. Wrenger, C. Betzel Scientific Reports 12, 4313 (14 pp) (2022) |
453 |
Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors M. Perbandt , N. Werner, A. Prester, H. Rohde , M. Aepfelbacher , W. Hinrichs, C. Betzel Scientific Reports 12, 5510 (12 pp) (2022) |
452 |
Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract S. Gevorgyan, R. Schubert, S. Falke, K. Lorenzen, K. Trchounian, C. Betzel Scientific Reports 12, 14077 (12 pp) (2022) |
451 |
Structural analysis of UBA5 and its binding partners S. Fuchs -/- Betreuer: C. Betzel Dissertation, Hamburg (2022) |
2021 | |
450 |
SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design V. Srinivasan, H. Brognaro, P. R. Prabhu, E. E. de Souza, S. Günther, P. Y. A. Reinke, T. J. Lane, H. Ginn, H. Han, W. Ewert, J. Sprenger, F. H. M. Koua, S. Falke, N. Werner, H. Andaleeb, N. Ullah, B. A. França, M. Wang, A. L. C. Barra, M. Perbandt , M. Schwinzer, C. Schmidt, L. Brings, K. Lorenzen, R. Schubert, R. R. G. Machado, E. D. Candido, D. B. L. Oliveira, E. L. Durigon, O. Yefanov, J. Lieske, L. Gelisio, M. Domaracky, P. Middendorf, M. Groessler, F. Trost, M. Galchenkova, S. Saouane, J. Hakanpää, M. Wolf, D. Turk, A. R. Pearson , H. N. Chapman , W. Hinrichs, C. Wrenger, A. Meents , C. Betzel bioRxiv 468943, 47 pp (2021) |
449 |
Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources S. C. Brandt, H. Brognaro, A. Ali, B. Ellinger, K. Maibach, M. Rühl, C. Wrenger, H. Schlüter , W. Schäfer, C. Betzel , S. Janssen, M. Gand Biotechnology for Biofuels 14, 74 (22 pp) (2021) |
448 |
Structural Dynamics and Perspectives of Vitamin B6 Biosynthesis Enzymes in Plasmodium: Advances and Open Questions A. L. C. Barra, N. Ullah, L. G. Morão, C. Wrenger, C. Betzel , A. S. Nascimento Frontiers in Cellular and Infection Microbiology 11, 688380 (11 pp) (2021) |
447 |
Editorial: From Apicomplexan Genes to Drug Discovery G. Wunderlich, C. Betzel , C. Wrenger Frontiers in Cellular and Infection Microbiology 11, 798754 (2 pp) (2021) |
446 |
Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane J. Knop, T. Lienemann, H. El Kilani, S. Falke, C. Krings, M. Sindalovskaya, J. Bergler, C. Betzel , S. Hoth International Journal of Molecular Sciences 22, 9455 (19 pp) (2021) |
445 |
The XBI BioLab for life science experiments at the European XFEL H. Han, E. Round, R. Schubert, Y. Gül, J. Makroczyova, D. Meza, P. Heuser, M. Aepfelbacher , I. Barák, C. Betzel , P. Fromme, I. Kursula, P. Nissen, E. Tereschenko, J. Schulz, C. Uetrecht, J. Ulicny, M. Wilmanns, J. Hajdu, V. S. Lamzin, K. Lorenzen Journal of Applied Crystallography 54, 7-21 (2021) |
444 |
Structure and dynamics of UBA5-UFM1 complex formation showing new insights in the UBA5 activation mechanism S. Fuchs, A. G. Kikhney, R. Schubert, C. Kaiser, E. Liebau, D. I. Svergun, C. Betzel , M. Perbandt Journal of Structural Biology 213, 107796 (2021) |
443 |
Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass A. Ali, B. Ellinger, S. C. Brandt, C. Betzel , M. Rühl, C. Wrenger, H. Schlüter , W. Schäfer, H. Brognaro, M. Gand Microorganisms 9, 1581 (25 pp) (2021) |
442 |
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S. Günther, P. Y. A. Reinke, Y. Fernández-García, J. Lieske, T. J. Lane, H. M. Ginn, F. H. M. Koua, C. Ehrt, W. Ewert, D. Oberthür , O. Yefanov, S. Meier, K. Lorenzen, B. Krichel, J.-D. Kopicki, L. Gelisio, W. Brehm, I. Dunkel, B. Seychell, H. Gieseler, B. Norton-Baker, B. Escudero-Pérez, M. Domaracky, S. Saouane, A. Tolstikova, T. A. White, A. Hänle, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, M. Barthelmeß , F. Schluenzen, P. L. Xavier, N. Werner, H. Andaleeb, N. Ullah, S. Falke, V. Srinivasan, B. A. França, M. Schwinzer, H. Brognaro, C. Rogers, D. Melo, J. J. Zaitseva-Doyle, J. Knoška, G. E. Peña-Murillo, A. R. Mashhour, V. Hennicke, P. Fischer, J. Hakanpää, J. Meyer, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, A. R. Beccari, G. Bourenkov, D. von Stetten, G. Pompidor, I. Bento, S. Panneerselvam, I. Karpics, T. R. Schneider, M. M. Garcia-Alai , S. Niebling, C. Günther, C. Schmidt, R. Schubert, H. Han, J. Boger, D. C. F. Monteiro, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. G. Feiler, M. S. Weiss, E.-C. Schulz, P. Mehrabi, K. Karnicar, A. Usenik, J. Loboda, H. Tidow , A. Chari, R. Hilgenfeld, C. Uetrecht, R. Cox, A. Zaliani, T. Beck , M. Rarey , S. Günther , D. Turk, W. Hinrichs, H. N. Chapman , A. R. Pearson , C. Betzel , A. Meents Science 372, 642-646 (2021) |
441 |
The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity N. Werner, K. Petersen, C. Vollstedt, P. P. Garcia, J. Chow, M. Ferrer, L. Fernandez-Lopez, S. Falke, M. Perbandt , W. Hinrichs, C. Betzel , W. R. Streit Scientific Reports 11, 12255 (14 pp) (2021) |
440 |
Eruca sativa seed napin structural insights and thorough functional characterization B. Khaliq, S. Falke, Q. Saeed, M. Bilal, A. Munawar, A. Ali, G. Baermann, H.-u.-R. Athar, S. Mahmood, C. Betzel , Q. Ali, A. Akrem Scientific Reports 11, 24066 (2021) |
439 |
Analyzing structure and function of an industrially important enzyme from Nectria haematococca for biofuel production H. Andaleeb -/- Betreuer: C. Betzel Dissertation, Hamburg (2021) |
438 |
Detecting nano-and micro-sized protein crystals via nonlinear optical imaging methods Q.-d. Cheng (= Q. Cheng) -/- Betreuer: C. Betzel Dissertation, Hamburg (2021) |
437 |
Structural and biophysical Analysis of plasmodial and bacterial multimeric Pdx1 - Pdx2 proteins and complexes N. Ullah -/- Betreuer: C. Betzel Dissertation, Hamburg (2021) |
436 |
Mechanism of drug resistance in Staphylococcus aureus and future drug discovery F. Wakasuqui, A. L. G. Lusa, S. Falke, C. Betzel , C. Wrenger Jenny Stanford Series on Biocatalysis 7, 259-280 (2021) |
2020 | |
435 |
Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease S. Günther, P. Y. A. Reinke, D. Oberthür , O. Yefanov, H. Ginn, S. Meier, T. J. Lane, K. Lorenzen, L. Gelisio, W. Brehm, I. Dunkel, M. Domaracky, S. Saouane, J. Lieske, C. Ehrt, F. H. M. Koua, A. Tolstikova, T. A. White, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, P. L. Xavier, M. Barthelmeß , F. Schluenzen, N. Werner, H. Andaleeb, N. Ullah, S. Falke, B. A. França, M. Schwinzer, H. Brognaro, B. Seychell, H. Gieseler, D. Melo, J. J. Zaitsev-Doyle, B. Norton-Baker, J. Knoška, G. Esperanza, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, C. Rogers, D. C. F. Monteiro, J. Hakanpää, J. Meyer, H. Noei, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. Feiler, M. Weiss, E.-C. Schulz, P. Mehrabi, C. Schmidt, R. Schubert, H. Han, B. Krichel, Y. Fernández-García, B. Escudero-Pérez, S. Günther , D. Turk, C. Uetrecht, T. Beck , H. Tidow , A. Chari, A. Zaliani, M. Rarey , R. Cox, R. Hilgenfeld, H. N. Chapman , A. R. Pearson , C. Betzel , A. Meents bioRxiv 043554 (17 pp) (2020) |
434 |
Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease S. Günther, P. Y. A. Reinke, Y. Fernández-García, J. Lieske, T. J. Lane, H. M. Ginn, F. H. M. Koua, C. Ehrt, W. Ewert, D. Oberthür , O. Yefanov, S. Meier, K. Lorenzen, B. Krichel, J.-D. Kopicki, L. Gelisio, W. Brehm, I. Dunkel, B. Seychell, H. Gieseler, B. Norton-Baker, B. Escudero-Pérez, M. Domaracky, S. Saouane, A. Tolstikova, T. A. White, A. Hänle, M. Groessler, H. Fleckenstein, F. Trost, M. Galchenkova, Y. Gevorkov, C. Li, S. Awel, A. Peck, M. Barthelmeß , F. Schluenzen, P. L. Xavier, N. Werner, H. Andaleeb, N. Ullah, S. Falke, V. Srinivasan, B. A. França, M. Schwinzer, H. Brognaro, C. Rogers, D. Melo, J. J. Zaitsev-Doyle, J. Knoška, G. E. P. Murillo, A. R. Mashhour, F. Guicking, V. Hennicke, P. Fischer, J. Hakanpää, J. Meyer, P. Gribbon, B. Ellinger, M. Kuzikov, M. Wolf, A. R. Beccari, G. Bourenkov, D. von Stetten, G. Pompidor, I. Bento, S. Panneerselvam, I. Karpics, T. R. Schneider, M. M. Garcia-Alai , S. Niebling, C. Günther, C. Schmidt, R. Schubert, H. Han, J. Boger, D. C. F. Monteiro, L. Zhang, X. Sun, J. Pletzer-Zelgert, J. Wollenhaupt, C. G. Feiler, M. S. Weiss, E.-C. Schulz, P. Mehrabi, K. Karnicar, A. Usenik, J. Loboda, H. Tidow , A. Chari, R. Hilgenfeld, C. Uetrecht, R. Cox, A. Zaliani, T. Beck , M. Rarey , S. Günther , D. Turk, W. Hinrichs, H. N. Chapman , A. R. Pearson , C. Betzel , A. Meents bioRxiv 378422v2, 36 pp (2020) |
433 |
Protein-crystal detection with a compact multimodal multiphoton microscope Q.-d. Cheng, H.-Y. Chung, R. Schubert, S.-H. Chia, S. Falke, C. N. Mudogo, F. X. Kärtner, G. Chang, C. Betzel Communications Biology 3, 569 (7 pp) (2020) |
432 |
Neuer Ansatz für Mittel gegen Schlafkrankheit C. Betzel CU - Chemie UniHamburg - Die Mitarbeiterzeitung (27) 7-7 (2020) |
431 |
Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1-Pdx2 Complex N. Ullah, H. Andaleeb, C. N. Mudogo, S. Falke, C. Betzel , C. Wrenger International Journal of Molecular Sciences 21, 5971 (16 pp) (2020) |
430 |
Novel approaches for the lipid sponge phase crystallization of the Rhodobacter sphaeroides photosynthetic reaction center G. Selikhanov, T. Fufina, L. Vasilieva, C. Betzel , A. G. Gabdulkhakov IUCrJ 7, 1084-1091 (2020) |
429 |
Molecular characterization of a ghrelin-L-aptamer complex C. Schmidt, M. Perbandt , S. Klussmann, C. Betzel Journal of Molecular Structure 1204, 127510 (2020) |
428 |
A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism H. Büttner, M. Perbandt , T. Kohler, A. Kikhney, M. Wolters, M. Christner, M. Heise, J. Wilde, S. Weißelberg, A. Both, C. Betzel , S. Hammerschmidt, D. I. Svergun, M. Aepfelbacher , H. Rohde mBio 11, e01612-20 (19 pp) (2020) |
427 |
In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors K. Nass, L. Redecke , M. Perbandt , O. Yefanov, M. Klinge, R. Koopmann, F. Stellato, A. G. Gabdoulkhakov, R. Schönherr, D. Rehders , J. M. Lahey-Rudolph, A. Aquila, A. Barty, S. Basu, R. B. Doak, R. Duden, M. Frank, R. Fromme, S. Kassemeyer, G. Katona, R. A. Kirian , H. Liu, I. V. Majoul, J. M. Martin-Garcia, M. Messerschmidt, R. L. Shoeman, U. Weierstall, S. Westenhoff, T. A. White, G. J. Williams, C. H. Yoon, N. A. Zatsepin, P. Fromme, M. Duszenko, H. N. Chapman , C. Betzel Nature Communications 11, 620 (13 pp) (2020) |
426 |
High-resolution crystal structure and biochemical characterization of a GH11 endoxylanase from Nectria haematococca H. Andaleeb, N. Ullah, S. Falke, M. Perbandt , H. Brognaro, C. Betzel Scientific Reports 10, 15658 (13 pp) (2020) |
425 |
Pulsed electric fields induce modulation of protein liquid-liquid phase separation M. Wang, S. Falke, R. Schubert, K. Lorenzen, Q.-d. Cheng, C. Exner, H. Brognaro, C. N. Mudogo, C. Betzel Soft Matter 16, 8547-8553 (2020) |
424 |
Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles A. Manuwar, B. Dreyer, A. Böhmert, A. Ullah, Z. Mughal, A. Akrem, S. A. Ali, H. Schlüter , C. Betzel Toxins 12, 669 (41 pp) (2020) |
423 |
Reply to Comments on Proteomic Investigations of Two Pakistani Naja Snake Venom Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles. Toxins 2020, 12, 669 A. Munawar, B. Dreyer, H. Schlüter , C. Betzel Toxins 12, 781 (3 pp) (2020) |
422 |
Protein phase separation and determinants of in cell crystallization C. N. Mudogo, S. Falke, H. Brognaro, M. Duszenko, C. Betzel Traffic 21, 220-230 (2020) |
421 |
Analyse von Struktur und Dynamik ausgewählter Enzyme und potenzieller Wirkstofftargets unter Anwendung gepulster Synchrotron- und X-FEL Strahlung N. Werner -/- Betreuer: C. Betzel Dissertation, Hamburg (2020) |
2019 | |
420 |
Multi-step concanavalin a phase separation and early-stage nucleation monitored via dynamic and depolarized light scattering H. Brognaro, S. Falke, C. N. Mudogo, C. Betzel Crystals 9, 620 (14 pp) (2019) |
419 |
Forschungsprojekt AK Betzel: Zelluläre Determinaten der Kondensation von Tau Proteinen C. Betzel CU - Chemie UniHamburg - Die Mitarbeiterzeitung (25) 13-13 (2019) |
418 |
Hochdurchsatz Serielle-Femtosekunden-Kristallographie@EU XFEL C. Betzel CU - Chemie UniHamburg - Die Mitarbeiterzeitung (26) 16-16 (2019) |
417 |
Effect of macromolecular mass transport in microgravity protein crystallization A. Martirosyan, L. J. DeLucas, C. Schmidt, M. Perbandt , D. McCombs, M. Cox, C. Radka, C. Betzel Gravitational and Space Research 7, 33-44 (2019) |
416 |
A
multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation S. Falke, H. Brognaro, A. Martirosyan, K. Dierks, C. Betzel Heliyon 5, e03016 (8 pp) (2019) |
415 |
Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer L. Konczalla, D. R. Perez, N. Wenzel, G. Wolters-Eisfeld, C. Klemp, J. Lüddeke, A. Wolski, D. Landschulze, C. Meier , A. Buchholz, D. Yao, B. T. Hofmann, J. K. Graß, S. L. Spriestersbach, K. Grupp, U. Schumacher, C. Betzel , S. Kapis, T. Nuguid, P. Steinberg, K. Püschel, G. Sauter, M. Bockhorn, F. G. Uzunoglu, J. R. Izbicki, C. Güngör, A. T. el Gammal International Journal of Cancer 146, 1618-1630 (2019) |
414 |
Structural characterization of 12S seed cruciferin from Eruca sativa in solution applying small-angle X-ray scattering B. Khaliq, S. Falke, S. Iqbal, F. Buck, S. Mahmood, Z. Ali, M. Ahmad, A. Wahid, C. Betzel , A. Akrem Pakistan Journal of Botany 51, 1387-1394 (2019) |
413 |
Cm3+/Eu3+ induced structural, mechanistic and functional implications for calmodulin B. Drobot, M. Schmidt, Y. Mochizuki, T. Abe, K. Okuwaki, F. Brulfert, S. Falke, S. A. Samsonov, Y. Komeiji, C. Betzel , T. Stumpf, S. Tsushima Physical Chemistry Chemical Physics 21, 21213-21222 (2019) |
412 |
Enzyme activity and structural features of three single-domain phloem cyclophilins from Brassica napus P. Hanhart, S. Falke, M. Garbe, V. Rose, M. Thieß, C. Betzel , J. Kehr Scientific Reports 9, 9368 (13 pp) (2019) |
411 |
The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity Among Snake Venom Phosphodiesterases A. Ullah, K. Ullah, H. Ali, C. Betzel , S. ur Rehman Toxins 11, 625 (24 pp) (2019) |
410 |
Effect of macromolecular mass transport in microgravity vs 1G protein crystallization A. Martirosyan -/- Betreuer: C. Betzel Dissertation, Hamburg (2019) |
409 |
Structural and biochemical analysis of selected nucleic acid-protein complexes C. Schmidt -/- Betreuer: C. Betzel Dissertation, Hamburg (2019) |
408 |
Dynamic Light Scattering (DLS). Principles, Perspectives, Applications to Biological Samples S. Falke, C. Betzel -/- Herausgeber: A. S. Pereira, P. Tavares, P. Limão-Vieira Radiation in Bioanalysis 173-193 (2019) |
2018 | |
407 |
Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate V. V. Balaev, I. I. Prokofev, A. G. Gabdoulkhakov, C. Betzel , A. A. Lashkov Acta Crystallographica, Section F: Structural Biology Communications 74, 193-197 (2018) |
406 |
The conserved hypothetical protein Tb427.10.13790 is required for cytokinesis in Trypanosoma brucei C. N. Mudogo, S. F. Werner, S. Mogk, C. Betzel , M. Duszenko Acta Tropica 188, 34-40 (2018) |
405 |
Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis P. R. Prabhu, S. D. Moorthy, J. Madhumathi, S. N. Pradhan, M. Perbandt , C. Betzel , P. Kaliraj Biochemical and Biophysical Research Communications 505, 979-984 (2018) |
404 |
Structural and Functional Analysis of Pyrimidine Nucleoside Phosphorylases of the NP-I and NP-II Families in Complexes with 6-Methyluracil I. I. Prokofev, A. A. Lashkov, A. G. Gabdoulkhakov, V. V. Balaev, A. S. Mironov, C. Betzel , A.'b. M. Mikhailov Crystallography Reports 63, 418-427 (2018) |
403 |
Forschungsverbund InfectoPhysics - neue Mittel gegen Antibiothikaresistenzen C. Betzel CU - Chemie UniHamburg - Die Mitarbeiterzeitung (24) 6-6 (2018) |
402 |
Spider's venom phospholipases D: A structural review R. Masood, K. Ullah, H. Ali, I. Ali, C. Betzel , A. Ullah International Journal of Biological Macromolecules 107, 1054-1065 (2018) |
401 |
Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action A. Ullah, R. Masood, I. Ali, K. Ullah, H. Ali, H. Akbar, C. Betzel International Journal of Biological Macromolecules 114, 788-811 (2018) |
400 |
De novo protein structure determination by heavy-atom soaking in lipidic cubic phase and SIRAS phasing using serial synchrotron crystallography S. Botha, D. Baitan, K. E. J. Jungnickel, D. Oberthür , C. Schmidt, S. Stern, M. O. Wiedorn, M. Perbandt , H. N. Chapman , C. Betzel IUCrJ 5, 524-530 (2018) |
399 |
Highly affine and selective aptamers against cholera toxin as capture elements in magnetic bead-based sandwich ELAA E. G. Frohnmeyer, F. Frisch, S. Falke, C. Betzel , M. Fischer Journal of Biotechnology 269, 35-42 (2018) |
398 |
Isolation and initial structural characterization of a 27 kDa protein from Zingiber officinale S. Rasheed, M. S. Ahmad, S. Falke, A. Arslan, R. Fazel, H. Schlüter , C. Betzel , M. I. Choudhary Journal of Molecular Structure 1156, 330-335 (2018) |
397 |
Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12 S. Falke, K. Dierks, C. Blanchet, M. Gräwert, F. Cipriani, R. Meijers, D. I. Svergun, C. Betzel Journal of Synchrotron Radiation 25, 361-372 (2018) |
396 |
Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography Y. Gicquel, R. Schubert, S. Kapis, G. Bourenkov, T. Schneider, M. Perbandt , C. Betzel , H. N. Chapman , M. Heymann Journal of Visualized Experiments 134, e57133 (14 pp) (2018) |
395 |
Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering D. Baitan, R. Schubert, A. Meyer, K. Dierks, M. Perbandt , C. Betzel Journal of Visualized Experiments 138, e57070 (11 pp) (2018) |
394 |
Crystal Structure of Mistletoe Lectin I (ML-I) from Viscum album in Complex with 4-N-Furfurylcytosine at 2.85 Å Resolution M. S. Ahmad, S. Rasheed, S. Falke, B. Khaliq, M. Perbandt , M. I. Choudhary, W. T. Markiewicz, J. Barciszewski, C. Betzel Medicinal Chemistry 14, 754-763 (2018) |
393 |
Megahertz serial crystallography M. O. Wiedorn, D. Oberthür , R. Bean, R. Schubert, N. Werner, B. Abbey, M. Aepfelbacher , L. Adriano, A. Allahgholi, N. Al-Qudami, J. Andreasson, S. Aplin, S. Awel, K. Ayyer, S. Bajt, I. Barák, S. Bari, J. Bielecki, S. Botha, D. Boukhelef, W. Brehm, S. Brockhauser, I. Cheviakov, M. A. Coleman, F. Cruz-Mazo, C. Danilevski, C. Darmanin, R. B. Doak, M. Domaracky, K. Dörner, Y. Du, H. Fangohr, H. Fleckenstein, M. Frank, P. Fromme, A. M. Gañán-Calvo, Y. Gevorkov, K. Giewekemeyer, H. M. Ginn, H. Graafsma, R. Graceffa, D. Greiffenberg, L. Gumprecht, P. Göttlicher, J. Hajdu, S. Hauf, M. Heymann, S. Holmes, D. A. Horke, M. S. Hunter, S. Imlau, A. Kaukher, Y. Kim, A. Klyuev, J. Knoška, B. Kobe, M. Kuhn, C. Kupitz, J. Küpper , J. M. Lahey-Rudolph, T. Laurus, K. L. Cong, R. Letrun, P. L. Xavier, L. Maia, F. R. N. C. Maia, V. Mariani, M. Messerschmidt, M. Metz, D. Mezza, T. Michelat, G. Mills, D. C. F. Monteiro, A. J. Morgan, K. Mühlig, A. Munke, A. Münnich, J. Nette, K. A. Nugent, T. Nuguid, A. M. Orville, S. Pandey, G. Pena, P. Villanueva-Perez, J. Poehlsen, G. Previtali, L. Redecke , W. M. Riekehr, H. Rohde , A. Round, T. Safenreiter, I. Sarrou, T. Sato, M. Schmidt, B. Schmitt, R. Schönherr, J. Schulz, J. A. Sellberg, M. M. Seibert, C. Seuring , M. L. Shelby, R. L. Shoeman, M. Sikorski, A. Silenzi, C. A. Stan, X. Shi, S. Stern, J. Sztuk-Dambietz, J. Szuba, A. Tolstikova, M. Trebbin , U. Trunk, P. Vagovic, T. Ve, B. Weinhausen, T. A. White, K. Wrona, C. Xu, O. Yefanov, N. A. Zatsepin, J. Zhang, M. Perbandt , A. P. Mancuso, C. Betzel , H. N. Chapman , A. Barty Nature Communications 9, 4025 (11 pp) (2018) |
392 |
Snake Venom Peptides: Tools of Biodiscovery A. Munawar, S. A. Ali, A. Akrem, C. Betzel Toxins 10, 474 (29 pp) (2018) |
391 |
Analyzing crystal growth phenomena and mechanisms for the production and optimization of protein crystals for serial crystallography (Analyse von Kristallwachstums Phänomene und der Mechanismes zur Produktion und Optimierung von Proteinkristallen für serielle Kristallografie ) D. Baitan (= D.-P. Baitan) -/- Betreuer: C. Betzel Dissertation, Hamburg (2018) |
390 |
Developing methods towards the structure determination of biological particles using crystallographic and single particle imaging techniques (Methodenweiterentwicklung für das Abbilden einzelner biologischer Partikel durch kohärente Diffraktion und Methodenentwicklung für serielle Kristallografie) S. Botha -/- Betreuer: C. Betzel Dissertation, Hamburg (2018) |
389 |
Structural and biophysical characterization of selected proteins associated with cyclically transmitted parasitic diseases S. Kapis -/- Betreuer: C. Betzel Dissertation, Hamburg (2018) (2018 wurde die Dissertation abgeschlossen. Druckdatum ist 2017) |
388 |
Strukturbasiertes Prodrug-Design C. Betzel , C. Wrenger Update Antibiotikaresistenz: Entstehung, Epidemiologie, Wirkstoffentwicklung 84-92 (2018), ISBN 978-3-7692-7113-3 , Verlag: Deutscher Apotheker Verlag |
2017 | |
387 |
Real-Time Observation of Protein Dense Liquid Cluster Evolution during Nucleation in Protein Crystallization R. Schubert, A. Meyer, D. Baitan, K. Dierks, M. Perbandt , C. Betzel Crystal Growth & Design 17, 954-958 (2017) Erratum: Crystal Growth & Design 17, 3579-3579 (2017) |
386 |
Experimente zum Kristallwachstum auf der ISS C. Betzel CU - Chemie UniHamburg - Die Mitarbeiterzeitung (21) 4-5 (2017) |
385 |
Protein profile analysis of two Australian snake venoms by one-dimensional gel electrophoresis and MS/MS experiments D. N. Georgieva, D. Hildebrand, R. Simas, M. A. Coronado, M. Kwiatkowski, H. Schlüter , R. K. Arni, P. J. Spencer, C. Betzel Current Medicinal Chemistry 24, 1892-1908 (2017) |
384 |
Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus J. Liu, S. Falke, B. Drobot, D. Oberthür , A. Kikhney, T. Guenther, K. Fahmy, D. I. Svergun, C. Betzel , J. Raff European Biophysics Journal 46, 77-89 (2017) |
383 |
SAXS and other spectroscopic analysis of 12S cruciferin isolated from the seeds of Brassica nigra B. Khaliq, S. Falke, A. Negm, F. Buck, A. Munawar, M. Saqib, S. Mahmood, M. S. Ahmad, C. Betzel , A. Akrem Journal of Molecular Structure 1137, 60-66 (2017) |
382 |
The functional role of Ataxia-telangiectasia mutated (ATM) gene in DNA double-strand break repair hierarchy A. Bakr -/- Betreuer: C. Betzel Dissertation, Hamburg (2017) |
381 |
Structural characterization of small basic protein (Sbp) and accumulation associated protein (Aap) - two proteins involved in biofilm formation in Staphylococcus epidermidis M. Fayyaz -/- Betreuer: C. Betzel , H. Rohde Dissertation, Hamburg (2017) |
380 |
Biotechnology, Cell Biology and Microgravity G. Ruyters, C. Betzel , D. Grimm Biotechnology in Space 1-10 (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
379 |
Protein Crystallization in Space: Early Successes and Drawbacks in the German Space Life Sciences Program G. Ruyters, C. Betzel Biotechnology in Space 11-26 (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
378 |
Protein Crystallization on the International Space Station ISS C. Betzel , A. Martirosyan, G. Ruyters Biotechnology in Space 27-39 (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
377 |
Drug Design C. Betzel , A. Martirosyan Biotechnology in Space 41-58 (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
376 |
Outlook: Future Potential of Biotechnology Research in Space G. Ruyters, M. Braun, C. Betzel , D. Grimm Biotechnology in Space 107-109 (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
375 |
Biotechnology in Space G. Ruyters, C. Betzel , D. Grimm SpringerBriefs in Space Life Sciences 109 pp (2017), ISBN 978-3-319-64053-2 , Verlag: Springer International Publishing |
374 |
Measurement cell for SAXS measurements and for dynamic light-scattering measurements D. I. Svergun, C. Blanchet, D. Franke, M. Gräwert, F. Cipriani, R. Meijers, K. Dierks, A. Eckhardt, A. Meyer, C. Betzel , S. Falke -/- Anmelder: European Molecular Biology Laboratory, Xtalconcepts GmbH, Universität Hamburg Patent: WO 2017067971 (A1) 2017-04-27; EP 3159674 (A1) 2017-04-26 |