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Universität Hamburg Fachbereich Chemie


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Publikationen seit 2005

2005
Riedel A., Leopold C.S. Quantification of omeprazole degradation by enteric polymers: an UV-VIS spectroscopy study. Pharmazie 60, 126-130 (2005).
Riedel A., Leopold C.S. Degradation of omeprazole induced by enteric polymer solutions and aqueous dispersions: HPLC investigations. Drug Dev. Ind. Pharm. 31, 149–158 (2005).
2006
Stroyer A., McGinity J.W., Leopold C.S. Solid state interactions between the proton pump inhibitor omeprazole and various enteric coating polymers. J. Pharm. Sci. 95, 1342-1353 (2006).
Remane Y., Leopold C.S. Transfer of the experimental methodology described in the FDA Guidance for corticosteroid bioequivalence testing to pharmacodynamic effects caused by nicotinates. J. Cosmet. Dermatol. 5, 289-293 (2006).
Remane Y., Leopold C.S., Maibach, H.I. Percutaneous penetration of methyl nicotinate from ointments using the Laser Doppler technique: Bioequivalence and enhancer effects. J. Pharmacokin. Pharmacodyn. 33, 719-735 (2006).
Remane Y., Leopold C. Time of erythema onset after application of methyl nicotinate ointments as response parameter: Influence of penetration kinetics and enhancing agents. Skin Pharmacol. Physiol. 19, 303-310 (2006).
2007
Leopold C.S. Aktuelles zur Pflastertechnologie unter spezieller Berücksichtigung des Rotigotinpflasters. Akt. Neurol. 34, Suppl. 4, S284-S289 (2007).
Schäfer U.F., Lippold B.C., Leopold C.S. Formulation issues; In: Dermal Absorption and Toxicity Assessment (Eds. Roberts M.S., Walters K.A.), 2nd ed., Informa Healthcare, London (2007).
2008
Wiedersberg S., Leopold C.S., Guy R.H. Bioavailability and bioequivalence of topical glucocorticoids. Eur. J. Pharm. Biopharm. 68, 453-466 (2008).
2009
Wiedersberg S., Naik A., Leopold C.S., Guy R.H. Pharmacodynamics and dermatopharmacokinetics of betamethasone 17-valerate: Assessment of topical bioavailability. Br. J. Dermatol. 160, 676-686 (2009).
Wiedersberg S., Leopold C.S., Guy R.H. Dermatopharmacokinetics of betamethasone 17-valerate: Influence of formulation viscosity and skin surface cleaning procedure. Eur. J. Pharm. Biopharm. 71, 362-366 (2009).
Wiedersberg S., Leopold C.S., Guy R.H. Effect of various vehicles on skin hydration in vivo. Skin Pharmacol. Physiol. 22, 128-130 (2009).
Ploen J., Andersch J., Heschel M., Leopold C.S. Citric acid as pH-modifying additive in an extended release pellet formulation containing a weakly basic drug. Drug Dev. Ind. Pharm. 35, 1210-1218 (2009).
Farag Y., Leopold C.S. Physicochemical properties of various shellac types. Dissolution Technol. 16, 33-39 (2009).
Jost W.H., Leopold C.S. Grundlagen der Pflasterapplikation von Wirkstoffen beim Parkinson-Syndrom. Akt. Neurol. 36, Suppl. 4, S1-S6 (2009).
2010
Gasch J., Oertel R., Leopold C.S., Knoth H. Contamination of 0.2 µm infusion filters by N,N-dimethylacrylamide. J. Critical Care 25, 172.e9-172.e14 (2010).
2011
Nokhodchi A., Hentzschel C.M., Leopold C.S. Drug release from liquisolid systems: speed it up, slow it down. Expert Opin. Drug Deliv. 8, 1-15 (2011).
Farag Y., Leopold C.S. Investigation of drug release from pellets coated with different shellac types. Drug Dev. Ind. Pharm. 37, 193-200 (2011).
Farag Y., Leopold C.S. Influence of the inlet air temperature in a fluid bed coating process on drug release from shellac coated pellets. Drug Dev. Ind. Pharm. 37, 320-328 (2011).
Farag Y., Leopold C.S. Development of shellac-coated sustained release pellet formulations. Eur. J. Pharm. Sci. 42, 400-405 (2011).
Hentzschel C.M., Sakmann, A., Leopold C.S. Suitability of various excipients as carrier and coating materials for liquisolid compacts. Drug Dev. Ind. Pharm. 37, 1200-1207 (2011).
Hentzschel C.M., Sakmann, A., Leopold C.S. Comparison of traditional and novel tableting excipients – Physical and compaction properties. Pharm. Dev. Technol., DOI:10.3109/10837450.2011.572897 (2011).
Gasch J., Leopold C.S., Knoth H. Drug retention by inline filters - Effect of positively charged polyethersulfone filter membranes on drug solutions with low concentration. Eur. J. Pharm. Sci. 44, 49-56 (2011).
Hentzschel C.M., Alnaief M., Smirnova I., Sakmann A., Leopold C.S. Enhancement of griseofulvin release from hydrophilic aerogel formulations and liquisolid compacts. Eur. J. Pharm. Biopharm., DOI:10.1016/j.ejpb.2011.08.001 (2011).
Hentzschel C.M., Alnaief M., Smirnova I., Sakmann A., Leopold C.S. Tableting properties of silica aerogel and other silicates. Drug Dev. Ind. Pharm. (2011), angenommen.
Alnaief M., Antonyuk S., Hentzschel C.M., Leopold C.S., Heinrich S., Smirnova I. A Novel Process for Coating of Silica Aerogel Microspheres for Controlled Drug Release Applications. Micropor. Mesopor. Mat. (2011), eingereicht.
Farag Y., Weidner S., Leopold C.S. Mimicking the aging p rocess of shellac by thermal treatment. Pharm. Dev. Technol. (2011), eingereicht.
Rehder S., Klukkert M., Löbmann K. A. M., Strachan C. J., Sakmann A., Gordon K., Rades T., Leopold C. S. Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding. Pharmaceutics, 3(4), 706-722 (2011).
Rehder S., Wu J. X., Laackmann J., Moritz H.-U., Rantanen J., Rades T., Leopold C. S. Real-time monitoring of solid-state phase transformations in acoustically levitated particles using near infrared and Raman spectroscopy, eingereicht
2012
Rehder S., Sakmann A., Rades T., Leopold C.S. Thermal degradation of amorphous glibenclamide. Eur. J. Pharm. Biopharm., 80 (1), 203-208 (2012).

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