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Universität Hamburg Fachbereich Chemie



Inhalt:

Kurzbiographie

2000 Promotion bei Jürgen Martens in Oldenburg
2000-2001 Alexander von Humboldt Postdoctoral Fellow bei Daniel S. Kemp, MIT
2001-2006 Habilitand an der Universität Hamburg
2006-2011 Professor an der Universität Giessen
2011- Professor für pharmazeutische Chemie an der Universität Hamburg

Weitere Informationen

Publikationen

 
2012
59 Synthesis of multivalent host and guest molecules for the construction of multithreaded diamide pseudorotaxanes
Nora L. Löw, Egor V. Dzyuba, Boris Brusilowskij, Lena Kaufmann, Elisa Franzmann, Wolfgang Maison, Emily Brandt, Daniel Aicher, Arno Wiehe, Christoph A. Schalley
Beilstein Journal of Organic Chemistry 8, 234-245 (2012)
58 3.1 Amino Acid Derived Auxiliaries: Amino Acids as Chiral Auxiliaries
Wolfgang Maison
Comprehensive Chirality 3 (Synthetic Methods II - Chiral Auxiliaries) 1-18 (2012)
57 Enzymatic allylic oxidations with a lyophilisate of the edible fungus Pleurotus sapidus
Aljona Rickert, Verena Krombach, Oliver Hamers, Holger Zorn, Wolfgang Maison
Green Chemistry 14, 639-644 (2012)
56 Untersuchung der Wirkung anthocyanhaltiger Säfte auf die Metabolisierug von Lactose-[13C,15N2]-Ureid
Georg Abel, Christian Borsch, Silvia Rudloff, Wolfgang Maison, Reinhard G. Bretzel, Clemens Kunz
Proceedings of the German Nutrition Society 17 (Abstracts zum 49. Wissenschaftlichen Kongress) 30-30 (V 1-2) (2012)
(49. Wissenschaftlicher Kongress der Deutschen Gesellschaft für Ernährung, 14.-16. März 2012, Freising)
 
2011
55 A Biomimetic Principle for the Chemical Modification of Metal Surfaces: Synthesis of Tripodal Catecholates as Analogues of Siderophores and Mussel Adhesion Proteins
Elisa Franzmann, Faiza Khalil, Christoph Weidmann, Michael Schröder, Marcus Rohnke, Jürgen Janek, Bernd M. Smarsly, Wolfgang Maison
Chemistry - A European Journal 17, 8596-8603 (2011)
54 Synthesis of Functionalized Benzoboroxoles for the Construction of Boronolectins
Falk Wienhold, Dorith Claes, Karolina Graczyk, Wolfgang Maison
Synthesis 4059-4067 (2011)
53 Synthesis of tripodal scaffolds as analogs of siderophore for stabilization of bimagnetic Fe/Fe3O4 core/shell nanoparticles for prostate tumor targeting applications
Faiza Khalil, Hongwang Wang, Sivasai Balivada, Wolfgang Maison, Stefan H. Bossmann
Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011, ORGN-369 (2011)
52 Pilotstudie zur intestinalen Metabolisierung von Lactose-13C,15N2-Ureid in vivo
Georg Abel, Christian Borsch, Silvia Rudloff, Wolfgang Maison, Reinhard G. Bretzel, Clemens Kunz
Proceedings of the German Nutrition Society 15 (Abstracts zum 48. Wissenschaftlichen Kongress) 103-103 (P 12-2) (2011)
(48. Wissenschaftlicher Kongress der Deutschen Gesellschaft für Ernährung, 16.-18. März 2011, Potsdam)
 
2010
51 An improved protocol for the preparation of (S)-vinylglycine from (S)-methionine
Christian-H. Küchenthal, Julia Migenda, Magdalena Polednia, Wolfgang Maison
Amino Acids 39, 443-448 (2010)
50 Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity
Valeria Pavet, Julien Beyrath, Christophe Pardin, Alexandre Morizot, Marie-Charlotte Lechner, Jean-Paul Briand, Miriam Wendland, Wolfgang Maison, Sylvie Fournel, Olivier Micheau, Gilles Guichard, Hinrich Gronemeyer
Cancer Research 70, 1101-1110 (2010)
49 Antibody Recruiting Small Molecules: a New Option for Prostate Tumor Therapy by PSMA Targeting
Christian-H. Küchenthal, Wolfgang Maison
ChemBioChem 11, 1052-1054 (2010)
48 Pd-Catalyzed Assembly of Spirooxindole Natural Products: A Short Synthesis of Horsfiline
Nina Deppermann, Heike Thomanek, Alexander H. G. P. Prenzel, Wolfgang Maison
Journal of Organic Chemistry 75, 5994-6000 (2010)
47 Synthesis of cyclic hydrazino α-carboxylic acids
Christian-H. Küchenthal, Wolfgang Maison
Synthesis 719-740 (2010)
46 Synthesis of novel carboxypeptidase ligands for tumor imaging
Christian-H. Küchenthal, Wolfgang Maison
Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010 MEDI-48 (2010)
45 Synthesis and development of multimeric molecules to mimic the pro-apoptotic ligand TRAIL, a member of the TNF superfamily
Marie-Charlotte Lechner, Julien Beyrath, Valeria Pavet, Christophe Pardin, Alexandre Morizot, Miriam Wendland, Wolfgang Maison, Olivier Micheau, Hinrich Gronemeyer, Sylvie Fournel, Gilles Guichard
Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010 MEDI-172 (2010)
 
2009
44 Multivalent Scaffolds for Affinity Maturation of Small Molecule Cell Surface Binders and Their Application to Prostate Tumor Targeting
Valerie Humblet, Preeti Misra, Kumar R. Bhushan, Khaled Nasr, Yao-Sen Ko, Takashi Tsukamoto, Nadine Pannier, John V. Frangioni, Wolfgang Maison
Journal of Medicinal Chemistry 52, 544-550 (2009)
43 Synthesis of Proline-Based Diketopiperazine Scaffolds
Nina Deppermann, Alexander H. G. P. Prenzel, Alexander Beitat, Wolfgang Maison
Journal of Organic Chemistry 74, 4267-4271 (2009)
42 Mimicking natural globular structures with rigid scaffolds based on adamantane
Nadine Pannier, John V. Frangioni, Wolfgang Maison
Advances in Experimental Medicine and Biology 611 (Peptides for Youth) 99-100 (2009)
41 Proline-based diketopiperazine-scaffolds
Nina Deppermann, Wolfgang Maison
Advances in Experimental Medicine and Biology 611 (Peptides for Youth) 203-204 (2009)
40 Multivalent peptidomimetics for tumor targeting
Nadine Pannier, Valerie Humblet, Preeti Misra, John V. Frangioni, Wolfgang Maison
Advances in Experimental Medicine and Biology 611 (Peptides for Youth) 403-404 (2009)
 
2008
39 Rigid C3-symmetric scaffolds based on adamantane
Nadine Pannier, Wolfgang Maison
European Journal of Organic Chemistry 1278-1284 (2008)
38 Rigid Multivalent Scaffolds Based on Adamantane
Khaled Nasr, Nadine Pannier, John V. Frangioni, Wolfgang Maison
Journal of Organic Chemistry 73, 1056-1060 (2008)
37 Noninvasive imaging of alphaVbeta6 integrin in fibrosis by multimerization of a nanomolar affinity 99m technetium-labeled small molecule
Preeti Misra, Kumar R. Bhushan, Popov Yuri, Nadine Pannier, Wolfgang Maison, Detlef Schuppan, John V. Frangioni
Abstracts of Papers, 235th ACS National Meeting, New Orleans, LA, United States, April 6-10, 2008, ORGN-316 (2008)
36 Synthesis of cyclic amines by pericyclic reactions involving C=N units
Wolfgang Maison
Science of Synthesis 40a, 343-363 (2008)
35 Product class 8: 1,2-Diazacyloalkanes
Wolfgang Maison
Science of Synthesis 40b, 1211-1252 (2008)
 
2007
34 Desymmetrization of 7-azabicycloalkenes by tandem olefin metathesis for the preparation of natural product scaffolds
Wolfgang Maison, Marina Büchert, Nina Deppermann
Beilstein Journal of Organic Chemistry 3, 48 (2007)
33 Azabicycloalkenes as synthetic intermediates - synthesis of conformationally constrained glutamate analogues
Wolfgang Maison
European Journal of Organic Chemistry 2276-2284 (2007)
32 Production of multimeric prostate-specific membrane antigen small-molecule radiotracers using a solid-phase 99mTc preloading strategy
Preeti Misra, Valerie Humblet, Nadine Pannier, Wolfgang Maison, John V. Frangioni
Journal of Nuclear Medicine 48, 1379-1389 (2007)
31 Production of multimeric prostate-specific membrane antigen small molecule radiotracers using a solid-phase 99mTc pre-loading strategy
Preeti Misra, Valerie Humblet, Nadine Pannier, Wolfgang Maison, John V. Frangioni
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007, INOR-066 (2007)
 
2006
30 Natural products research: renaissance with strengthened integration of biology and chemistry
Wolfgang Maison
Angewandte Chemie, International Edition 45, 3000-3002 (2006)
29 Azabicycloalkenes as Synthetic Intermediates: Application to the Preparation of Diazabicycloalkane Scaffolds
Alexander H. G. P. Prenzel, Nina Deppermann, Wolfgang Maison
Organic Letters 8, 1681-1684 (2006)
28 Azabicycloalkenes as Synthetic Intermediates - Synthesis of Azabicyclo[X.3.0]alkane Scaffolds
Marina Büchert, Sebastian Meinke, Alexander H. G. P. Prenzel, Nina Deppermann, Wolfgang Maison
Organic Letters 8, 5553-5556 (2006)
27 Preparation of substituted adamantanes with potential medical applications
John V. Frangioni, Wolfgang Maison, Daniel S. Kemp
Patent: US 20060063834 (A1) 2006-03-23
 
2005
26 Synthesis of modular dipeptide mimetics on the basis of diazabicycloalkanes and derivatives thereof with sulphur containing side chains
Daniel C. Grohs, Wolfgang Maison
Amino Acids 29, 131-138 (2005)
25 Stereoselective synthesis of aza- and diazabicyclo[X.Y.0]alkane dipeptide mimetics
Wolfgang Maison, Alexander H. G. P. Prenzel
Synthesis 1031-1048 (2005)
24 An improved cyclization protocol for the synthesis of diazabicyclo[4.3.0]alkanes
Daniel C. Grohs, Wolfgang Maison
Tetrahedron Letters 46, 4373-4376 (2005)
23 Synthesis of 1,4-diazabicyclo[X.Y.O]alkanes; scaffolds of dipeptide mimetics and proline derived natural products
Wolfgang Maison
Targets in Heterocyclic Systems 9, 87-113 (2005)
 
2004
22 Efficient synthesis of structurally diverse diazabicycloalkanes: scaffolds for modular dipeptide mimetics with tunable backbone conformations
Wolfgang Maison, Daniel C. Grohs, Alexander H. G. P. Prenzel
European Journal of Organic Chemistry 1527-1543 (2004)
21 Synthesis of Rigid Multivalent Scaffolds Based on Adamantane
Wolfgang Maison, John V. Frangioni, Nadine Pannier
Organic Letters 6, 4567-4569 (2004)
20 Synthesis and application of proline and pipecolic acid derivatives: tools for stabilization of peptide secondary structures
Wolfgang Maison -/- Herausgeber: Carsten Schmuck, Helma Wennemers
Highlights in Bioorganic Chemistry 18-29 (2004), Verlag: Wiley-VCH Verlag, Weinheim
19 Proline syn-anti isomerization, implications for protein folding
Wolfgang Maison -/- Herausgeber: Carsten Schmuck, Helma Wennemers
Highlights in Bioorganic Chemistry 29-30 (2004), Verlag: Wiley-VCH Verlag, Weinheim
 
2003
18 Improved chemical strategies for the targeted therapy of cancer
Wolfgang Maison, John V. Frangioni
Angewandte Chemie, International Edition 42, 4726-4728 (2003)
 
2002
17 Short and efficient synthesis of diazabicycloalkane dipeptide mimics
Wolfgang Maison, Daniela Küntzer, Daniel C. Grohs
Synlett 1795-1798 (2002)
16 A short stereoselective synthesis of disubstituted cyclic amino acids
Wolfgang Maison, Gunadi Adiwidjaja
Tetrahedron Letters 43, 5957-5960 (2002)
 
2001
15 Chaotropic anions strongly stabilize short, N-capped uncharged peptide helicies: A new look at the perchlorate effect
Wolfgang Maison, Robert J. Kennedy, Daniel S. Kemp
Angewandte Chemie, International Edition 40, 3819-3821 (2001)
14 Optimal N-Caps for N-Terminal Helical Templates: Effects of Changes in H-Bonding Efficiency and Charge
Wolfgang Maison, Eva Arce, Peter Renold, Robert J. Kennedy, Daniel S. Kemp
Journal of the American Chemical Society 123, 10245-10254 (2001)
13 Synthesis of novel pipecolic acid derivatives. Part 2. Addition of trimethylsilyl cyanide to 3,4,5,6-tetrahydropyridines
Ole Westerhoff, Arne Lützen, Wolfgang Maison, Marc Kosten, Jürgen Martens
Journal of the Chemical Society, Perkin Transactions 1, 508-513 (2001)
12 Diastereoselective Lewis acid mediated hydrophosphonylation of heterocyclic imines: a stereoselective approach towards α-amino phosphonates
Imre Schlemminger, Andreas Willecke, Wolfgang Maison, Rainer Koch, Arne Lützen, Jürgen Martens
Journal of the Chemical Society, Perkin Transactions 1, 2804-2816 (2001)
11 C-terminal helix capping propensities in a polyalanine context for amino acids bearing nonpolar aliphatic side chains
Wolfgang Maison, Robert J. Kennedy, Justin S. Miller, Daniel S. Kemp
Tetrahedron Letters 42, 4975-4977 (2001)
 
2000
10 Multicomponent synthesis of novel amino acid-nucleobase chimeras: a versatile approach to PNA-monomers
Wolfgang Maison, Imre Schlemminger, Ole Westerhoff, Jürgen Martens
Bioorganic & Medicinal Chemistry 8, 1343-1360 (2000)
9 Concept of Improved Rigidity: How to Make Enantioselective Hydrophosphonylation of Cyclic Imines Catalyzed by Chiral Heterobimetallic Lanthanoid Complexes Almost Perfect
Imre Schlemminger, Yoshinobu Saida, Harald Gröger, Wolfgang Maison, Nathalie Durot, Hiroaki Sasai, Masakatsu Shibasaki, Jürgen Martens
Journal of Organic Chemistry 65, 4818-4825 (2000)
8 Multicomponent synthesis of tripeptides containing pipecolic acid derivatives: selective induction of cis- and trans-imide bonds into peptide backbones
Wolfgang Maison, Arne Lützen, Marc Kosten, Imre Schlemminger, Ole Westerhoff, Wolfgang Saak, Jürgen Martens
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry 1867-1871 (2000)
7 Highly diastereoselective hydrophosphonylation of cyclic imines using BINOL as source of chirality
Imre Schlemminger, Arne Lützen, Andreas Willecke, Wolfgang Maison, Rainer Koch, Wolfgang Saak, Jürgen Martens
Tetrahedron Letters 41, 7285-7288 (2000)
6 Synthesis of the first enantiomerically pure 3-thiazolines via Asinger reaction
Imre Schlemminger, Hans-Hermann Janknecht, Wolfgang Maison, Wolfgang Saak, Jürgen Martens
Tetrahedron Letters 41, 7289-7292 (2000)
5 Efficient Synthesis of Amino acid Derivatives, Useful for the Preparation of Peptide Nucleic Acids, Unnatural Peptides and Peptide Mimetics
Wolfgang Maison -/- Betreuer: Jürgen Martens
Dissertation, Oldenburg (2000)
4 Preparation of precursors for PNA monomers
Jürgen Martens, Wolfgang Maison, Imre Schlemminger, Ole Westerhoff, Harald Gröger
Patent: WO 2000002864 (A1) 2000-01-20
 
1999
3 Modified PNAs: a simple method for the synthesis of monomeric building blocks
Wolfgang Maison, Imre Schlemminger, Ole Westerhoff, Jürgen Martens
Bioorganic & Medicinal Chemistry Letters 9, 581-584 (1999)
2 The synthesis of novel cyclic β-amino acids as intermediates for the preparation of bicyclic β-lactams
Wolfgang Maison, Marc Kosten, Audrey Charpy, Jürgen Kintscher-Langenhagen, Imre Schlemminger, Arne Lützen, Ole Westerhoff, Jürgen Martens
European Journal of Organic Chemistry 2433-2441 (1999)
1 Synthesis of novel pipecolic acid derivatives: a multicomponent approach from 3,4,5,6-tetrahydropyridines
Wolfgang Maison, Arne Lützen, Marc Kosten, Imre Schlemminger, Ole Westerhoff, Jürgen Martens
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry 3515-3525 (1999)

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