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Inhalt:
2012 | |
| 192 |
Evaluation of Deoxyhypusine Synthase Inhibitors Targeting BCR-ABL Positive Leukemias Patrick Ziegler, Tuhama Chahoud, Thomas Wilhelm, Nora Pällman, Melanie Braig, Valeska Wiehle, Susanne Ziegler, Marcus Schröder, Chris Meier, Adrian Kolodzik, Matthias Rarey, Jens Panse, Joachim Hauber, Stefan Balabanov, Tim H. Brümmendorf Investigational New Drugs 30, Online First (2012) |
| 191 |
Desoxyhypusin-Synthase Inhibitoren Chris Meier, Marcus Schröder, Mathias Rarey, Adrian Kolodzik, Joachim Hauber, Poomima Priyadarshini, Marcel Krepstakies Patent: DE 10 2012 103 405.2 |
2011 | |
| 190 |
Diastereoselective Synthesis of cycloSaligenyl-Nucleosyl-Phosphotriesters Edwuin Hander Rios Morales, Jan Balzarini, Chris Meier Chemistry - A European Journal 17, 1649-1659 (2011) |
| 189 |
Solid-Phase Synthesis of (Poly)phosphorylated Nucleosides and Conjugates Viktoria Caroline Tonn, Chris Meier Chemistry - A European Journal 17, 9832-9842 (2011) |
| 188 |
Synthesis of 2',3'-Modified Carbocyclic L-Nucleoside Analogues Sönke Jessel, Chris Meier European Journal of Organic Chemistry 1702-1713 (2011) |
| 187 |
Linear Synthesis of Chiral cycloSal-Pronucleotides Edwuin Hander Rios Morales, Cristina Arbelo Román, Jens Oliver Thomann, Chris Meier European Journal of Organic Chemistry 4397-4408 (2011) |
| 186 |
Diastereoselective Synthesis of (Aryloxy)phosphoramidate Prodrugs Cristina Arbelo Román, Philip Wasserthal, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 4899-4909 (2011) |
| 185 |
Synthesis of Nonnatural Nucleoside Diphosphate Sugars Saskia Wolf, Rosmirt Molina Berrio, Chris Meier European Journal of Organic Chemistry 6304-6313 (2011) |
| 184 |
Preventing Fusarium Head Blight of Wheat and Cob Rot of Maize by Inhibition of Fungal Deoxyhypusine Synthase Mayada Woriedh, Ilona Hauber, Ana Lilia Martinez-Rocha, Christian Voigt, Frank J. Maier, Marcus Schröder, Chris Meier, Joachim Hauber, Wilhelm Schäfer Molecular Plant-Microbe Interactions 24, 619-627 (2011) |
2010 | |
| 183 |
A Chemoenzymatic Synthesis of Carbocyclic Nucleosides and Nucleotides Miriam Mahler, Bastian Reichardt, Jan Balzarini, Chris Meier Antiviral Research 86, A61-A61 (2010) |
| 182 |
D-carba-dT as a Promising New Antiviral Compounds? Chris Meier, Bastian Reichardt, Svenja Warnecke, Miriam Mahler, Stephen Hughes, Paul L. Boyer Antiviral Research 86, A62-A62 (2010) |
| 181 |
Nucleoside Diphosphate Prodrugs of Antivirally Active Nucleosides Florian Pertenbreiter, Chris Meier Antiviral Research 86, A64-A64 (2010) |
| 180 |
First Diastereoselective Synthesis of Pronucleotides Edwuin Hander Rios Morales, Cristina Arbelo Román, Jan Balzarini, Chris Meier Antiviral Research 86, A65-A66 (2010) |
| 179 |
Rational Drug Design-Screening and Synthesis of Potential Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication Marcus Schröder, Adrian Kolodzik, Björn Windshügel, Marcel Krepstakies, Poornima Priyadarshini, Matthias Rarey, Joachim Hauber, Chris Meier Antiviral Research 86, A67-A67 (2010) |
| 178 |
Lipophilic Nucleoside Diphosphate Prodrugs - Synthesis and Properties Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 86, A67-A68 (2010) |
| 177 |
Stereoselective Synthetic Strategy to Potentially Antiviral Active Carbocyclic L-Nucleosides and L-Nucleotides Claudia Worthmann, Sönke Jessel, Jan Balzarini, Chris Meier Antiviral Research 86, A69-A70 (2010) |
| 176 |
A convenient synthesis of nucleoside diphosphate glycopyranoses and other polyphosphorylated bioconjugates Saskia Wolf, Tanja Zismann, Nathalie Lunau, Svenja Warnecke, Silke Wendicke, Chris Meier European Journal of Cell Biology 89, 63-75 (2010) |
| 175 |
Diastereoselective Synthesis of Aryloxy Phosphoramidate Prodrugs of 3'-Deoxy-2',3'-didehydrothymidine Monophosphate Cristina Arbelo Román, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 53, 7675-7681 (2010) |
| 174 |
Method for producing phosphate-bridged nucleoside conjugates Chris Meier, Saskia Wolf, Svenja Warnecke Patent: WO 2010015245 (A1) 2010-02-11; DE 102008044914 (A1) 2010-02-11 |
| 173 |
Procedure for the solid-state-supported production of phosphate-bridged nucleoside conjugates Chris Meier, Viktoria Caroline Tonn Patent: WO 2010127666 (A1) 2010-11-11; DE 102009020261 (A1) 2010-11-11 |
2009 | |
| 172 |
cycloSaligenyl-di-d4TMP: Highly Loaded cycloSal-pronucleotides that Release Two Equivalents of Nucleotides and Leaving One Masking Unit Chris Meier, Nicolas Gisch, Christian Ducho, Jan Balzarini Antiviral Research 82, A61-A61 (2009) |
| 171 |
Synthesis and Properties of cycloSal-phosphatetriesters of Fluorescent Bicyclic Nucleoside Analogues (BCNAS) Florian Pertenbreiter, Chris Meier Antiviral Research 82, A62-A62 (2009) |
| 170 |
Bioreversible Protection of Nucleosidediphosphates - Synthesis and Properties Tilmann Schulz, Henning Jacob Jessen, Jan Balzarini, Chris Meier Antiviral Research 82, A63-A63 (2009) |
| 169 |
Reliable Synthesis of Various Nucleoside Diphosphate Glycopyranoses Saskia Wolf, Tanja Zismann, Nathalie Lunau, Chris Meier Chemistry - A European Journal 15, 7656-7664 (2009) |
| 168 |
Doubly Loaded cycloSaligenyl-Pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphates) Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 52, 3464-3473 (2009) |
| 167 |
The Nucleoside Analogue D-carba T Blocks HIV-1 Reverse Transcription Paul L. Boyer, B. Christie Vu, Zandrea Ambrose, John G. Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E. Marquez, Stephen H. Hughes Journal of Medicinal Chemistry 52, 5356-5364 (2009) |
| 166 |
Synthesis of Nucleoside Di- and Triphosphates and Dinucleoside Polyphosphates with cycloSal-Nucleotides Svenja Warnecke, Chris Meier Journal of Organic Chemistry 74, 3024-3030 (2009) |
| 165 |
Synthesis of new cyclic and acyclic 5-halouridine derivatives as potential antiviral agents Mohamed Fathy Elshehry, Jan Balzarini, Chris Meier Synthesis 841-847 (2009) |
| 164 |
Improved process for preparation of enantiopure phosphorus(III) and phosphorus(V) compounds, such as phosphoric derivatives by asymmetric nucleophilic substitution of chiral phosphoramide dichloride auxiliary Chris Meier, Jens Oliver Thomann Patent: WO 2009121347 (A1) 2009-10-08 |
| 163 |
Lipophilic masked benzyl esters of nucleoside diphosphates and triphosphates as enzymatically hydrolyzable prodrugs for treatment of viral diseases, AIDS and cancers. Chris Meier, Henning Jacob Jessen Patent: WO 2009129798 (A2) 2009-10-29; DE 102008020633 (A1) 2009-10-29 |
2008 | |
| 162 |
Efficient synthesis of nucleoside diphosphate glycopyranoses Silke Wendicke, Svenja Warnecke, Chris Meier Angewandte Chemie, International Edition 47, 1500-1502 (2008) Translated: Angewandte Chemie 120, 1523-1525 (2008) |
| 161 |
Bioreversible protection of nucleoside diphosphates Henning Jacob Jessen, Tilmann Schulz, Jan Balzarini, Chris Meier Angewandte Chemie, International Edition 47, 8719-8722 (2008) Translated: Angewandte Chemie 120, 8847-8850 (2008) |
| 160 |
Anti-BK virus activity of nucleoside analogs Parmjeet Randhawa, Jiri Zemlicka, Andreas Sauerbrei, Chris Meier, Karl Y. Hostetler, James R. Beadle, Noush Afarin Farasati, Yuchen Huang, Matthews Bradley Antimicrobial Agents and Chemotherapy 52, 1519-1521 (2008) |
| 159 |
Enzyme-triggered cycloSal-Pronucleotides Chris Meier, Henning Jacob Jessen, Nicolas Gisch, Jan Balzarini Antiviral Research 78, A26-A26 (2008) |
| 158 |
Carbocyclic L-Nucleoside Analogues as Potential Antiviral Agents Sönke Jessel, Chris Meier Antiviral Research 78, A58-A58 (2008) |
| 157 |
A Synthetic Strategy to Different Cyclopentenyl-Nucleosides Bastian Reichardt, Chris Meier Antiviral Research 78, A62-A63 (2008) |
| 156 |
Synthesis and Properties of Glycosyl-functionalised cycloSal-Pronucleotides Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 78, A63-A63 (2008) |
| 155 |
Synthesis of DNA strands site-specifically damaged by C8-arylamine purine adducts and effects on various DNA polymerases Nicolas Böge, Maike I. Jacobsen, Zita Szombati, Sabrina Baerns, Francesca Di Pasquale, Andreas Marx, Chris Meier Chemistry - A European Journal 14, 11194-11208 (2008) |
| 154 |
Intracellular Trapping of cycloSal-Pronucleotides: Modification of Prodrugs with Amino Acid Esters Henning Jacob Jessen, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 6592-6598 (2008) |
| 153 |
Studies on Enzyme-Cleavable Dialkoxymethyl-cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphates Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 6752-6760 (2008) |
| 152 |
5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine Monophosphates, a Second Type of New, Enzymatically Activated cycloSaligenyl Pronucleotides Nicolas Gisch, Florian Pertenbreiter, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 51, 8115-8123 (2008) |
| 151 |
Nucleoside diphosphate prodrugs Chris Meier, Henning Jacob Jessen, Jan Balzarini Nucleic Acids Symposium Series 52, 83-84 (2008) |
| 150 |
Synthesis of C8-N-acetylarylamine 2'-dG-adducts and their site-specifically incorporation into oligonucleotides Sarah Krüger, Chris Meier Nucleic Acids Symposium Series 52, 307-308 (2008) |
| 149 |
Oligonucleotides damaged with carcinogenic aromatic amines at the C8- and N6-position of 2'-deoxyadenosine Maike I. Jacobsen, Chris Meier Nucleic Acids Symposium Series 52, 439-440 (2008) |
| 148 |
Improved synthesis of nucleoside diphosphate glycopyranoses Tanja Zismann, Chris Meier Nucleic Acids Symposium Series 52, 563-564 (2008) |
| 147 |
New efficient synthesis of nucleoside diphosphate glycopyranoses Saskia Wolf, Chris Meier Nucleic Acids Symposium Series 52, 579-580 (2008) |
| 146 |
New and efficient synthesis of nucleoside polyphosphates and nucleoside monophosphate sugars Svenja Warnecke, Chris Meier Nucleic Acids Symposium Series 52, 583-584 (2008) |
| 145 |
Carbocyclic L-nucleoside analogs as potential antiviral agents Sönke Jessel, Chris Meier Nucleic Acids Symposium Series 52, 615-616 (2008) |
| 144 |
The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase Sabine Specht, Salem Ramadan Sarite, Ilona Hauber, Joachim Hauber, Ulf Görbig, Chris Meier, Dorian Bevec, Achim Hoerauf, Annette Kaiser Parasitology Research 102, 1177-1184 (2008) |
| 143 |
First route to phosphoramidites of N2-hydrazinoaryl- and N2-azoaryl-dG adducts and their site-selective incorporation into DNA oligonucleotides Nicolas Böge, Marcus Schröder, Chris Meier Synlett 1066-1070 (2008) |
| 142 |
Synthesis of N2- and C8-N-Ac-DNA-adducts of aromatic amines Nicolas Böge, Sarah Krüger, Chris Meier Collection of Czechoslovak Chemical Communications, Collection Symposium Series 10, 137-141 (2008) |
2007 | |
| 141 |
Properties of Aminoacid Esters Linked to cycloSal-Pronucleotides Henning Jacob Jessen, Jan Balzarini, Chris Meier Antiviral Research 74, A73-A73 (2007) |
| 140 |
Bis-cycloSal-d4T-monophosphates: Drugs That Deliver Two Molecules of Bioactive Nucleotides Christian Ducho, Ulf Görbig, Sönke Jessel, Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 50, 1335-1346 (2007) |
| 139 |
Enzymatically Activated cycloSal-d4T-monophosphates: The Third Generation of cycloSal-Pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Journal of Medicinal Chemistry 50, 1658-1667 (2007) |
| 138 |
Synthesis of DNA-Oligonucleotides Damaged by Arylamine-Modified 2'-Deoxyguanosine Nicolas Böge, Zita Szombati, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 705-708 (2007) |
| 137 |
Intracellular Trapping of cycloSal-Pronucleotides by Enzymatic Cleavage Henning Jacob Jessen, Viktoria Caroline Tonn, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 827-830 (2007) |
| 136 |
New cycloAMB-Nucleoside Phosphonate Prodrugs Ulf Görbig, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 831-834 (2007) |
| 135 |
5-Diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 861-864 (2007) |
| 134 |
A New and Short Convergent Synthetic Strategy to Carbocyclic Nucleosides Bastian Reichardt, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 935-937 (2007) |
| 133 |
Cyclopentane-Nucleobase Coupling in the Synthesis of Carbocyclic L-Nucleosides: is A SN2-Reaction an Alternative to the Mitsunobu-Reaction? Sönke Jessel, Elena Hense, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1181-1184 (2007) |
| 132 |
Synthesis of C8-Modified 2'-Deoxyadenosine with Carcinogenic Arylamines Maike I. Jacobsen, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1217-1220 (2007) |
| 131 |
New Developments of the "Lock-in" Modified cycloSal-d4TMPs Dalibor Vukadinovic-Tenter, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 26, 1325-1328 (2007) |
| 130 |
A new short and efficient synthetic route to C8-N-acetylarylamine 2'-deoxyguanosine phosphoramidites Nicolas Böge, Sarah Krüger, Marcus Schröder, Chris Meier Synthesis 3907-3914 (2007) |
2006 | |
| 129 |
Inhibitory efficacy of cycloSal-nucleoside monophosphates of aciclovir and brivudin on DNA synthesis of orthopoxviruses Andreas Sauerbrei, Chris Meier, Astrid Meerbach, Peter Wutzler Antiviral Chemistry & Chemotherapy 17, 25-31 (2006) |
| 128 |
Stereoselective Synthesis and Biological Evaluation of D- and L-carba-Nucleosides as Potential Antiviral Agents Chris Meier, Sönke Jessel, Bastian Reichardt, Olaf Rudolf Ludek, Jan Balzarini Antiviral Research 70, A27 (2006) |
| 127 |
cycloSal-Monophosphate Prodrugs with an Optimized Mask Ulf Görbig, Anne Baum, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 126 |
Enzymatically Activated cycloSal-Pronucleotides Nicolas Gisch, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 125 |
Synthesis and Properties of Intrinsically Fluorescent cycloSal-Pronucleotides Henning Jacob Jessen, Wolfgang Fendrich, Tilmann Schulz, Jan Balzarini, Chris Meier Antiviral Research 70, A60 (2006) |
| 124 |
Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules Chris Meier, Jan Balzarini Antiviral Research 71, 282-292 (2006) |
| 123 |
New and efficient synthesis of racemic cyclopent-3-en-1-yl nucleoside analogues and their derivatives Bastian Reichardt, Olaf Rudolf Ludek, Chris Meier Collection of Czechoslovak Chemical Communications 71, 1011-1028 (2006) |
| 122 |
Second-generation cycloSal-d4TMP pronucleotides bearing esterase-cleavable sites - the "trapping" concept Chris Meier, Christian Ducho, Henning Jacob Jessen, Dalibor Vukadinovic-Tenter, Jan Balzarini European Journal of Organic Chemistry 197-206 (2006) |
| 121 |
Synthesis and properties of fluorescent cycloSal nucleotides m5K and its 2',3'-dideoxy analog dm5K Henning Jacob Jessen, Wolfgang Fendrich, Chris Meier European Journal of Organic Chemistry 924-931 (2006) |
| 120 |
Synthesis and antiviral evaluation of carbocyclic 3'-azidothymidine (AZT) analogs and their cycloSal-phosphate triesters Olaf Rudolf Ludek, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 932-940 (2006) |
| 119 |
Influence of the N3-protection group on N1- vs. O2-alkylation in the Mitsunobu reaction Olaf Rudolf Ludek, Chris Meier European Journal of Organic Chemistry 941-946 (2006) |
| 118 |
cycloSal phosphates as chemical Trojan horses for intracellular nucleotide and glycosyl-monophosphate delivery - chemistry meets biology Chris Meier European Journal of Organic Chemistry 1081-1102 (2006) |
| 117 |
Antiviral activity of cycloSaligenyl prodrugs of the nucleoside analogue bromovinyldeoxyuridine against herpes viruses Astrid Meerbach, Chris Meier, Andreas Sauerbrei, Heide-Marie Meckel, Peter Wutzler International Journal of Antimicrobial Agents 27, 423-430 (2006) |
| 116 |
Synthesis and Properties of Oligonucleotides Containing C8-Deoxyguanosine Arylamine Adducts of Borderline Carcinogens Nicolas Böge, Sonja Gräsl, Chris Meier Journal of Organic Chemistry 71, 9728-9738 (2006) |
| 115 |
Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction - part II: influence of the solvent on N1- versus O2-alkylation Olaf Rudolf Ludek, Chris Meier Synlett 324-326 (2006) |
| 114 |
First synthesis of C8-arylamine adducts of 2'-deoxyadenosine and incorporation of the phosphoramidite into an oligonucleotide Maike I. Jacobsen, Chris Meier Synlett 2411-2414 (2006) |
| 113 |
Divergent synthesis and biological evaluation of carbocyclic α-, iso- and 3'-epi-nucleosides and their lipophilic nucleotide prodrugs Olaf Rudolf Ludek, Tobias Krämer, Jan Balzarini, Chris Meier Synthesis 1313-1324 (2006) |
| 112 |
The cycloSal-Nucleotide Delivery System - Development of Chemical Trojan Horses as Antiviral Agents Chris Meier -/- Herausgeber: Godefridus J. Peters Deoxynucleoside Analogs in Cancer Chemotherapy 353-401 (2006) |
2005 | |
| 111 |
A Possible Synthetic Strategy to Diastereomerically Pure cycloSal-Prodrugs Jens Oliver Thomann, Katharina Wallach, Edwuin Hander Rios Morales, Chris Meier Antiviral Research 65, A93 (2005) |
| 110 |
Novel "Lock-in" Modified cycloSal Nucleotides (I): Variations of the Linker Moiety Dalibor Vukadinovic, Chris Meier, Jan Balzarini Antiviral Research 65, A93 (2005) |
| 109 |
cycloAmb Nucleoside Phosphonates: Nucleoside Phosphonate Prodrugs Based on the cycloSal Concept Ulf Görbig, Jan Balzarini, Chris Meier Antiviral Research 65, A94 (2005) |
| 108 |
In vitro activity of cycloSal-nucleoside monophosphates and polyhydroxycarboxylates against orthopoxviruses Andreas Sauerbrei, Chris Meier, Astrid Meerbach, M. Schiel, Björn Helbig, Peter Wutzler Antiviral Research 67, 147-154 (2005) |
| 107 |
Antivirale Aktivität von Phenolkörperpolymerisaten und cycloSaligenyl-Pronucleotiden gegen ein SARS-assoziiertes Coronavirus (Antiviral activity of phenolic polymers and cycloSaligenyl-pronucleotides towards SARS-related Coronavirus) Michaela Schmidtke, Chris Meier, Michael Schacke, Björn Helbig, Vadim Makarov, Holger F. Rabenau, Jindrich Cinatl, Peter Wutzler Chemotherapie Journal 14 (1) 16-21 (2005) |
| 106 |
cycloSal-pronucleotides of brivudine monophosphate - highly active antiviral agents Chris Meier, Astrid Meerbach, Peter Wutzler Current Medicinal Chemistry: Anti-Infective Agents 4, 317-335 (2005) |
| 105 |
cycloSal-PMEA and cycloAmb-PMEA: Potentially New Phosphonate Prodrugs Based on the cycloSal-Pronucleotide Approach Chris Meier, Ulf Görbig, Hanns Christian Müller, Jan Balzarini Journal of Medicinal Chemistry 48, 8079-8086 (2005) |
| 104 |
Novel cycloSal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase Christian Ducho, Sönke Jessel, Nicolas Gisch, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 519-522 (2005) |
| 103 |
Synthesis of carbocyclic nucleotides as potential substrates for thymidylate kinase Olaf Rudolf Ludek, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 683-686 (2005) |
| 102 |
Synthesis of oligonucleotides bearing an arylamine modification in the C8-position of 2'-deoxyguanosine Chris Meier, Sonja Gräsl, Ilka Detmer, Andreas Marx Nucleosides, Nucleotides & Nucleic Acids 24, 691-694 (2005) |
| 101 |
"Lock-in" modified cycloSal nucleotides - the second generation of cycloSal prodrugs Dalibor Vukadinovic, Nicolas Böge, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 24, 939-942 (2005) |
| 100 |
Synthesis of carbocyclic pyrimidine nucleosides using the Mitsunobu reaction - part I: influence of the alcohol on N1- versus O2-alkylation. Olaf Rudolf Ludek, Chris Meier Synlett 3145-3147 (2005) |
| 99 |
Esterase-cleavable cycloSal-pronucleotides - the trapping concept Chris Meier, Christian Ducho, Henning Jacob Jessen, Jan Balzarini Collection of Czechoslovak Chemical Communications, Collection Symposium Series 7, 105-113 (2005) |
2004 | |
| 98 |
Are Cholinesterases Inhibited by cycloSal-Nucleotides? Chris Meier, Christian Ducho, Jan Balzarini Antiviral Research 62, A85 (2004) |
| 97 |
cycloSaligenyl-mannose-1-monophosphates as a new strategy in CDG-Ia therapy: hydrolysis, mechanistic insights and biological activity Ulrike Muus, Christian Kranz, Thorsten Marquardt, Chris Meier European Journal of Organic Chemistry 1228-1235 (2004) |
| 96 |
cycloSal-pronucleotides - development of first and second generation chemical Trojan horses for antiviral chemotherapy Chris Meier, Astrid Meerbach, Jan Balzarini Frontiers in Bioscience 9, 873-890 (2004) |
| 95 |
Interaction of cycloSal-Pronucleotides with Cholinesterases from Different Origins. A Structure-Activity Relationship Chris Meier, Christian Ducho, Ulf Görbig, Robert Esnouf, Jan Balzarini Journal of Medicinal Chemistry 47, 2839-2852 (2004) |
| 94 |
"Lock-in"-cycloSal-pronucleotides - a new generation of chemical Trojan horses? Chris Meier, Manuel F. H. Ruppel, Dalibor Vukadinovic, Jan Balzarini Mini-Reviews in Medicinal Chemistry 4, 383-394 (2004) |
| 93 |
Second Generation of cycloSal-Pronucleotides with Esterase-Cleavable Sites: The "Lock-In"-Concept Chris Meier, Manuel F. H. Ruppel, Dalibor Vukadinovic, Jan Balzarini Nucleosides, Nucleotides & Nucleic Acids 23, 89-115 (2004) |
| 92 |
cycloSal-pronucleotides-design of the concept, chemistry, and antiviral activity Chris Meier -/- Herausgeber: Erik de Clercq Advances in Antiviral Drug Design 4, 147-213 (2004) |
2003 | |
| 91 |
"Lock-in"-Modified cycloSal-d4TMP and -BVdUMP Triesters - Extention of a Pronucleotide System Chris Meier, Manuel F. H. Ruppel, Dalibor Vukadinovic, Astrid Meerbach, Peter Wutzler, Erik de Clercq, Jan Balzarini Antiviral Research 57, A39 (2003) |
| 90 |
A Short and Efficient Route Towards Enantiomerically Pure Carbocyclic Analogues of Thymidine: New Substrates for Thymidylate Kinase? Olaf Rudolf Ludek, Jan Balzarini, Chris Meier Antiviral Research 57, A54 (2003) |
| 89 |
Interaction of Cholinesterases with cycloSal- Nucleotides Christian Ducho, Jan Balzarini, Chris Meier Antiviral Research 57, A54 (2003) |
| 88 |
Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy Cristina Mazzon, Chiara Rampazzo, Maria Chiara Scaini, Lisa Gallinaro, Anna Karlsson, Chris Meier, Jan Balzarini, Peter Reichard, Vera Bianchi Biochemical Pharmacology 66, 471-479 (2003) |
| 87 |
Structures of Human Thymidylate Kinase in Complex with Prodrugs: Implications for the Structure-Based Design of Novel Compounds Nils Ostermann, Dario Segura-Peña, Chris Meier, Thomas Veit, Christian Monnerjahn, Manfred Konrad, Arnon Lavie Biochemistry 42, 2568-2577 (2003) |
| 86 |
Antiviral effects of cycloSaligenyl-pronucleotides towards Herpes simplex virus and Epstein-Barr virus Astrid Meerbach, Renate Klöcking, Claudia Friedrichs, Peter Wutzler, Chris Meier Chemotherapie Journal 12 (3) 79-84 (2003) |
| 85 |
3,5-Di-(tert-butyl)-6-fluoro-cycloSal-d4TMP - a pronucleotide with a considerably improved masking group Christian Ducho, Silke Wendicke, Ulf Görbig, Jan Balzarini, Chris Meier European Journal of Organic Chemistry 4786-4791 (2003) |
| 84 |
Synthesis of Carbocyclic Analogues of Thymidine Olaf Rudolf Ludek, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 683-685 (2003) |
| 83 |
Study of Different Substituted Cyclic and Acyclic Benzylpronucleotides of d4T Relative to Their Hydrolytic Stability and Antiviral Activity Ulrike Muus, Erik de Clercq, Jan Balzarini, Lieve Naesens, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 791-795 (2003) |
| 82 |
Novel Nucleotide Analogues as Potential Substrates for TMPK, a Key Enzyme in the Metabolism of AZT Hanns Christian Müller, Chris Meier, Jan Balzarini, Jochen Reinstein Nucleosides, Nucleotides & Nucleic Acids 22, 821-823 (2003) |
| 81 |
d4TMP Delivery from 7-Substituted cycloSal-d4TMPs Chris Meier, Jürgen Renze, Jan Balzarini, Erik de Clercq Nucleosides, Nucleotides & Nucleic Acids 22, 825-827 (2003) |
| 80 |
Non-inhibition of acetylcholinesterase by cycloSal nucleotides Christian Ducho, Jan Balzarini, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 841-843 (2003) |
| 79 |
Synthesis of Oligonucleotide Building Blocks of 2'-Deoxyguanosine Bearing a C8-Arylamine Modification Sonja Gräsl, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1119-1121 (2003) |
| 78 |
α-Hydroxybenzylphosphonate Modified Oligonucleotides: Synthesis, Properties, and a Novel Route via Monomer Building Blocks Andreas Hohlfeld, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1123-1125 (2003) |
| 77 |
Determination of the Absolute P-Configuration of a Phthalidyl-Phosphonate Thymidine-Thymidine Dimer Wolfgang Fendrich, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 22, 1127-1129 (2003) |
| 76 |
New convergent synthesis of carbocyclic nucleoside analogues Olaf Rudolf Ludek, Chris Meier Synthesis 2101-2109 (2003) |
2002 | |
| 75 |
Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cycloSal-d4TMP - hydrolysis, mechanistic insights and anti-HIV activity Chris Meier, Ulrike Muus, Jürgen Renze, Lieve Naesens, Erik de Clercq, Jan Balzarini Antiviral Chemistry & Chemotherapy 13, 101-114 (2002) |
| 74 |
Aryl-substituted and benzo-annulated cycloSal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate - correlation of structure, hydrolysis properties and anti-HIV activity Christian Ducho, Jan Balzarini, Lieve Naesens, Erik de Clercq, Chris Meier Antiviral Chemistry & Chemotherapy 13, 129-141 (2002) |
| 73 |
Comparative Study of Different Benzyl-Pronucleotides of d4T: Hydrolytic Stability and Antiviral Activity Ulrike Muus, Chris Meier, Lieve Naesens, Erik de Clercq, Jan Balzarini Antiviral Research 53, A37 (2002) |
| 72 |
cycloSal-d4TMP pronucleotides-structural variations, mechanistic insights and antiviral activity Chris Meier, Jürgen Renze, Christian Ducho, Jan Balzarini Current Topics in Medicinal Chemistry 2, 1111-1121 (2002) |
| 71 |
cycloSal-BVDUMP Pronucleotides: How to Convert an Antiviral-Inactive Nucleoside Analogue into a Bioactive Compound against EBV Chris Meier, Andreas Lomp, Astrid Meerbach, Peter Wutzler Journal of Medicinal Chemistry 45, 5157-5172 (2002) |
| 70 |
cycloSal-pronucleotides - design of chemical Trojan horses Chris Meier Mini-Reviews in Medicinal Chemistry 2, 219-234 (2002) |
| 69 |
Formation of benzooxaphosphole oxide heterocyclic system by the ring-contractive Arbuzov-Michaelis isomerization of alkoxy-substituted benzodioxaphosphorins Eduard E. Nifantiev, Svetlana B. Khrebtova, Yulia V. Kulikova, Dmitrii A. Predvoditelev, Tat'yana S. Kukhareva, Pavel V. Petrovskii, Mirjam Rose, Chris Meier Phosphorus, Sulfur and Silicon and the Related Elements 177, 251-259 (2002) |
| 68 |
Highly efficient synthesis of a phosphoramidite building block of C8-deoxyguanosine adducts of aromatic amines Chris Meier, Sonja Gräsl Synlett 802-804 (2002) |
2001 | |
| 67 |
Antiviral activity of cycloSaligenyl prodrugs of acyclovir, carbovir, and abacavir Jan Balzarini, Friederike Haller-Meier, Erik de Clercq, Chris Meier Antiviral Chemistry & Chemotherapy 12, 301-306 (2001) |
| 66 |
Novel Synthetic Route Towards Cyclic and Acyclic Analogues of AZT Monophosphate (AZTMP) Hanns Christian Müller, Chris Meier, Erik de Clercq, Jan Balzarini, Jochen Reinstein Antiviral Research 50, A46 (2001) |
| 65 |
Hydrolysis Behavior of Benzyl-Functionalized cycloSal-d4TMPs Jürgen Renze, Chris Meier, Jan Balzarini, Erik de Clercq Antiviral Research 50, A47 (2001) |
| 64 |
cycloSal-BVDUMP Triesters - Synthesis, Properties and Anti-EBV Activity of New Potential Pronucleotides Chris Meier, Andreas Lomp, Astrid Meerbach, Peter Wutzler Antiviral Research 50, A60 (2001) |
| 63 |
cycloSaligenyl-5-[(E)-2-bromovinyl]-2'-deoxyuridine monophosphate (cycloSal-BVDUMP) pronucleotides active against Epstein-Barr virus Chris Meier, Andreas Lomp, Astrid Meerbach, Peter Wutzler ChemBioChem 2, 283-285 (2001) |
| 62 |
Synthesis, hydrolysis and anti-EBV activity of a series of 3'-modified cycloSal-BVDUMP pronucleotides Chris Meier, Andreas Lomp, Astrid Meerbach, Peter Wutzler Nucleosides, Nucleotides & Nucleic Acids 20, 307-314 (2001) |
| 61 |
Benzyl-functionalized cycloSal-d4T monophosphates Jürgen Renze, M. Plath, Christian Ducho, Jan Balzarini, Erik de Clercq, Chris Meier Nucleosides, Nucleotides & Nucleic Acids 20, 931-934 (2001) |
2000 | |
| 60 |
Inhibitory Effect of cycloSaligenyl-Nucleoside Monophosphates of Acyclic Nucleoside Analogues on HSV-1 and EBV Astrid Meerbach, Renate Klöcking, Chris Meier, Andreas Lomp, Björn Helbig, Peter Wutzler Antiviral Research 45, 69-77 (2000) |
| 59 |
Intracellular Metabolism of 3-Methyl-cycloSal-d4TMP and 3-Methyl-cycloSal-AZTMP: Same Concept but Different Antiviral Outcome Jan Balzarini, Tina Knispel, Lieve Naesens, Erik de Clercq, Chris Meier Antiviral Research 46, A46 (2000) |
| 58 |
Synthesis, Properties and Anti-EBV Activity of a New Series of 3'-Modified cycloSal-BVDUMP Pronucleotides Astrid Meerbach, Peter Wutzler, Andreas Lomp, Chris Meier Antiviral Research 46, A82 (2000) |
| 57 |
Interactions of Conformationally Biased North and South 2'-Fluoro-2',3'-dideoxynucleoside 5'-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase Lan Mu, Stefan G. Sarafianos, Marc C. Nicklaus, Pamela Russ, Maqbool A. Siddiqui, Harry Ford, Hiroaki Mitsuya, Richard Le, Eiichi Kodama, Chris Meier, Tina Knispel, Lynne Anderson, Joseph J. Barchi, Victor E. Marquez Biochemistry 39, 11205-11215 (2000) |
| 56 |
cycloSaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP Jan Balzarini, Stefano Aquaro, Tina Knispel, Chiara Rampazzo, Vera Bianchi, Carlo-Federico Perno, Erik de Clercq, Chris Meier Molecular Pharmacology 58, 928-935 (2000) |
| 55 |
Structures of Human Thymidylate Kinase in Complex with Nucleotides Nils Ostermann, Amon Lavie, Sreekanta Padiyar, Ralf Brundiers, Manfred Konrad, Axel Scheidig, Chris Meier, Jochen Reinstein, Thomas Veit, Roger Goody, Ilme Schlichting Hamburger Synchrotonstrahlungslabor HASYLAB am Deutschen Elektronen-Synchroton DESY. Jahresbericht 1999 II, 295-296 (2000) Alternativer Quellentitel: HASYLAB Annual Report |
1999 | |
| 54 |
cycloSal-Pronucleotides of 2',3'-Dideoxyadenosine and 2',3'-Dideoxy-2',3'-didehydroadenosine: Synthesis and Antiviral Evaluation of a Highly Efficient Nucleotide Delivery System Chris Meier, Tina Knispel, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 42, 1604-1614 (1999) |
| 53 |
cycloSal-Pronucleotides of 2'-Fluoro-ara- and 2'-Fluoro-ribo-2',3'-dideoxyadenosine as a Strategy to Bypass a Metabolic Blockade Chris Meier, Tina Knispel, Victor E. Marquez, Maqbool A. Siddiqui, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 42, 1615-1624 (1999) |
| 52 |
Intracellular Metabolism of cycloSaligenyl 3'-Azido-2',3'-dideoxythymidine Monophosphate, a Prodrug of 3'-Azido-2',3'-dideoxythymidine (Zidovudine) Jan Balzarini, Lieve Naesens, Stefano Aquaro, Tina Knispel, Carlo-Federico Perno, Erik de Clercq, Chris Meier Molecular Pharmacology 56, 1354-1361 (1999) |
| 51 |
cycloSal-2'-ara(ribo)-fluoro-2',3'-dideoxyadenosine monophosphates - an effort to solve the structure-activity relationship of 2'-fluoro-ddA Chris Meier, Tina Knispel, Victor E. Marquez, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 18, 907-912 (1999) |
| 50 |
Effects of cycloSal-d4TMP-Derivatives in H9 Cells with Induced AZT Resistanance Phenotype Bettina Gröschel, Chris Meier, R. Zehner, J. Cinatl, Hans W. Doerr, J. Cinatl Jr. Nucleosides & Nucleotides 18, 933-936 (1999) |
| 49 |
Phosphoramidite chemistry for the synthesis of cycloSal-pronucleotides Florence Mugnier, Chris Meier Nucleosides & Nucleotides 18, 941-942 (1999) |
| 48 |
Evidence for cyclophosphate formation during hydrolysis of 3-methyl-cycloSal-PCVMP Andreas Lomp, Chris Meier, Markus Herderich, Peter Wutzler Nucleosides & Nucleotides 18, 943-944 (1999) |
| 47 |
N,O-selectivity in the synthesis of 3-Me-cycloSal-ddAMP Tina Knispel, Chris Meier Nucleosides & Nucleotides 18, 945-946 (1999) |
| 46 |
A new cyclic phosphoramidate d4T prodrug approach cycloAmb-d4T-phosphoramidates Martina Lorey, Chris Meier Nucleosides & Nucleotides 18, 947-948 (1999) |
| 45 |
Elucidation of the hydrolytical properties of α-hydroxybenzylphosphonates as a new potential prooligonucleotide concept Ralf Peter Mauritz, Frank S. Schmelz, Chris Meier Nucleosides & Nucleotides 18, 1417-1418 (1999) |
1998 | |
| 44 |
Synthesis and Antiviral Evaluation of SATE-Foscarnet Prodrugs and New Foscarnet-AZT Conjugates Chris Meier, Anne-Marie Aubertin, M. de Monte, A. Faraj, Jean-Pierre Sommadoussi, Christian Perigaud, Jean-Louis Imbach, Gilles Gosselin Antiviral Chemistry & Chemotherapy 9, 41-51 (1998) |
| 43 |
Chemistry and Anti-Herpes SimplexVirus Type 1 Evaluation of cycloSal-Nucleotides of Acyclic Nucleoside Analogues Chris Meier, Lothar W. Habel, Friederike Haller-Meier, Andreas Lomp, Markus Herderich, Renate Klöcking, Astrid Meerbach, Peter Wutzler Antiviral Chemistry & Chemotherapy 9, 389-402 (1998) |
| 42 |
cycloSal-Nucleotides of 2',3'-Dideoxyadenosine Derivatives as Efficient Nucleotide Delivery Systems Chris Meier, Tina Knispel, Victor E. Marquez, Erik de Clercq, Jan Balzarini Antiviral Research 37, A63 (1998) |
| 41 |
Chemistry and Properties of cycloSaligenyl-Nucleotides (cycloSal-NMP) of Acyclic Nucleoside Analogues as Potential Anti-HSV Agents Chris Meier, Lothar W. Habel, Friedericke Meier, Peter Wutzler Antiviral Research 37, A75 (1998) |
| 40 |
Inhibitory Effect of cycloSaligenyl-Nucleoside Monophosphates (cycloSal-NMP) of Acyclic Nucleoside Analogues on HSV-1 and EBV Astrid Meerbach, Renate Klöcking, Chris Meier, Peter Wutzler Antiviral Research 37, A76 (1998) |
| 39 |
Nucleotide delivery from cycloSaligenyl-3'-azido-3'-deoxythymidine monophosphates (cycloSal-AZTMP) Chris Meier, Erik de Clercq, Jan Balzarini European Journal of Organic Chemistry 837-846 (1998) |
| 38 |
cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine Monophosphate (cycloSal-d4TMP): Synthesis and Antiviral Evaluation of a New d4TMP Delivery System Chris Meier, Martina Lorey, Erik de Clercq, Jan Balzarini Journal of Medicinal Chemistry 41, 1417-1427 (1998) |
| 37 |
Pronucleotides - Recent Advances in the Design of Efficient Tools for the Delivery of Biologically Active Nucleoside Monophosphates (Review) Chris Meier Synlett 233-242 (1998) |
1997 | |
| 36 |
Cyclic saligenyl phosphotriesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T). A new pronucleotide approach Chris Meier, Martina Lorey, Erik de Clercq, Jan Balzarini Bioorganic & Medicinal Chemistry Letters 7, 99-104 (1997) |
| 35 |
ADA-bypass by lipophilic cycloSal-ddAMP pronucleotides a second example of the efficiency of the cycloSal-concept Chris Meier, Tina Knispel, Erik de Clercq, Jan Balzarini Bioorganic & Medicinal Chemistry Letters 7, 1577-1582 (1997) |
| 34 |
Auf dem Weg zu neuen, nicht-enzymatisch spaltbaren Pro-Nucleotiden - Ziel ist, selektiv in den Proliferationszyklus der Viren einzugreifen (Towards new, non-enzymically cleavable pronucleotides) Chris Meier, Martina Lorey, Tina Knispel GIT Labor-Fachzeitschrift 41, 965-967 (1997) |
| 33 |
cycloSal-Pronucleotides: Design and Biological Evaluation of a New Class of Lipophilic Nucleotide Prodrugs Chris Meier, Tina Knispel, Martina Lorey, Jan Balzarini International Antiviral News 5, 183-185 (1997) |
| 32 |
Fpmp-protected α-hydroxyphosphonate diesters for the synthesis of prooligonucleotides Ralf Peter Mauritz, Chris Meier Nucleosides & Nucleotides 16, 675-678 (1997) |
| 31 |
New synthesis and antitumor activity of cycloSal-derivatives of 5-fluoro-2'-deoxyuridinemonophosphate Martina Lorey, Chris Meier, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 789-792 (1997) |
| 30 |
cycloSaligenyl-3'-azido-2',3'-dideoxythymidine monophosphate (cycloSal-AZTMP) - a new pronucleotide approach? Chris Meier, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 793-796 (1997) |
| 29 |
Synthesis of 3',5'-dithymidylyl-α-hydroxyphosphonate dimer building blocks for oligonucleotide synthesis - a new prooligonucleotide approach - Ralf Peter Mauritz, Chris Meier, Eugen Uhlmann Nucleosides & Nucleotides 16, 1209-1212 (1997) |
| 28 |
cycloSaligenyl-2',3'-dideoxy-2',3'-didehydroythymidinemonophosphate (cycloSal-D4TMP) - a new pronucleotide approach -. Chris Meier, Martina Lorey, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 1303-1306 (1997) |
| 27 |
cycloSaligenyl-5-fluoro-2'-deoxyuridinemonophosphate (cycloSal-FDUMP) - a new prodrug approach for FDUMP Martina Lorey, Chris Meier, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 16, 1307-1310 (1997) |
| 26 |
Di-ddU-α-hydroxyphosphonate and α-hydroxy-α-methylphosphonates as potential prodrugs of antiviral nucleoside analogs Lothar W. Habel, Chris Meier Nucleosides & Nucleotides 16, 1311-1314 (1997) |
| 25 |
Fast-atom bombardment mass spectrometric study of SATE Foscarnet prodrugs and of a series of Foscarnet-AZT conjugates Jef Rozenski, Chris Meier, Jean-Louis Aubagnac, Rene Astier, Piet Herdewijn, Jean-Louis Imbach, Gilles Gosselin Rapid Communications in Mass Spectrometry 11, 1212-1218 (1997) |
1996 | |
| 24 |
2-Nucleos-5'-O-yl-4H-1,3,2-benzodioxaphosphinin-2-oxides: A new concept for lipophilic, potential prodrugs of biologically active nucleoside monophosphates Chris Meier Angewandte Chemie, International Edition in English 35, 70-72 (1996) Translated: Angewandte Chemie 108, 77-796 (1996) |
| 23 |
4H-1.3.2-Benzodioxaphosphorine-2-nucleosyl-2-oxide - A New Concept for Lipophilic, Potential Prodrugs of 3'-Azidothymidine Chris Meier, Martina Lorey, Erik de Clercq, Jan Balzarini Antiviral Research 28, A29 (1996) |
| 22 |
Enantioselective synthesis of diisopropyl α-, β-, and γ-hydroxyarylalkylphosphonates from ketophosphonates: a study on the effect of the phosphonyl group Chris Meier, Wolfgang Hans Gerhardt Laux Tetrahedron 52, 589-598 (1996) |
| 21 |
Asymmetric synthesis of chiral, nonracemic dialkyl-.alpha.-hydroxyalkylphosphonates via a (-)-chlorodiisopinocampheylborane (Ipc2B-Cl) reduction Chris Meier, Wolfgang Hans Gerhardt Laux Tetrahedron: Asymmetry 7, 89-94 (1996) |
1995 | |
| 20 |
Book Review: A Nucleus of Modern Chemical Techniques: Advanced Organic Chemistry of Nucleic Acids. By Z. A. Shabarova and A. A. Bogdanov Chris Meier Angewandte Chemie, International Edition in English 34, 1523-1523 (1995) Translated: Angewandte Chemie 107, 1790-1791 (1995) |
| 19 |
Asymmetric synthesis of chiral, nonracemic dialkyl α-hydroxyarylmethyl- and α-, β-, and γ-hydroxyalkylphosphonates from keto phosphonates Chris Meier, Wolfgang Hans Gerhardt Laux, Jan W. Bats Liebigs Annalen 1963-1979 (1995) |
| 18 |
Lipophilic α-hydroxybenzylphosphonates as prodrugs of 3'-azido-2',3'-dideoxythymidine (AZT) Chris Meier, Lothar W. Habel, Jan Balzarini, Erik de Clercq Liebigs Annalen 2195-2202 (1995) |
| 17 |
5',5'-Di-O-nucleosyl-O'-benzylphosphotriesters as potential prodrugs of 3'-azido-2',3'-dideoxythymidine-5'-monophosphate Chris Meier, Lothar W. Habel, Jan Balzarini, Erik de Clercq Liebigs Annalen 2203-2208 (1995) |
| 16 |
Homo dinucleoside-α-hydroxyphosphonate diesters as prodrugs of the antiviral nucleoside analogs 2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine Chris Meier, Lothar W. Habel, Wolfgang Hans Gerhardt Laux, Erik de Clercq, Jan Balzarini Nucleosides & Nucleotides 14, 759-762 (1995) |
| 15 |
Synthesis of protected 3',5'-di-2'-deoxythymidine-(α-hydroxy-2-nitrobenzyl)-phosphonate diesters as dimer building blocks for oligonucleotides Chris Meier, Ralf Peter Mauritz Nucleosides & Nucleotides 14, 803-804 (1995) |
| 14 |
Asymmetric synthesis of chiral, nonracemic dialkyl-α-, β-, and γ-hydroxyalkylphosphonates via a catalyzed enantioselective catecholborane reduction. Chris Meier, Wolfgang Hans Gerhardt Laux Tetrahedron: Asymmetry 6, 1089-1092 (1995) |
| 13 |
Preparation of (arylhydroxymethyl)phosphonate esters of nucleoside analogs and related compounds as drugs Eugen Uhlmann, Chris Meier -/- Anmelder: Hoechst AG Patent: DE 4321946 (A1) 1995-01-12 |
1993 | |
| 12 |
5',5'-O-Dinucleoside (α-hydroxybenzyl)phosphonates as a lipophilic potential prodrugs of 2',3'-dideoxythymidine (ddT) Chris Meier Angewandte Chemie, International Edition in English 32, 1704-1706 (1993) Translated: Angewandte Chemie 105, 1854-1856 (1993) |
1992 | |
| 11 |
Peptide nucleic acids (PNA's): unusual properties of a nonionic oligonucleotide analog Chris Meier, Joachim W. Engels Angewandte Chemie, International Edition in English 31, 1008-1010 (1992) Translated: Angewandte Chemie 104, 1039-1041 (1992) |
| 10 |
O-Alkyl-5',5'-dinucleoside phosphates as prodrugs of 3'-azidothymidine and cordycepin Chris Meier, Jean Michel Neumann, Francois André, Yvette Henin, Huynh-Dinh Tam Journal of Organic Chemistry 57, 7300-7308 (1992) |
1991 | |
| 9 |
O-Alkyl-5',5'-dinucleoside phosphates as combined prodrugs of antiviral and antibiotic compounds Chris Meier, Huynh-Dinh Tam Bioorganic & Medicinal Chemistry Letters 1, 527-530 (1991) |
| 8 |
The modification of guanine nucleosides and nucleotides by the borderline arylamine carcinogens 4-methyl- and 4-methoxyaniline: chemistry and structural characterization Chris Meier, Gernot Boche Carcinogenesis 12, 1633-1640 (1991) |
| 7 |
Improved conversion of adenosine to 3'-deoxyadenosine Chris Meier, Huynh-Dinh Tam Synlett 227-228 (1991) |
1990 | |
| 6 |
N-Aryl-O-(α-aminoacyl)hydroxylamine: Modellreaktionen zur Aktivierung von monocyclischen aromatischen Aminen zu ultimaten Carcinogenen durch α-Aminosäuren (N-aryl-O-(α-aminoacyl)hydroxylamines: model reactions for the activation of monocyclic aromatic amines into ultimate carcinogens with α-amino acids) Chris Meier, Gernot Boche Chemische Berichte 123, 1691-1698 (1990) |
| 5 |
N-Aryl-O-(α-aminoacyl)hydroxylamine: Modellreaktionen mit Desoxyguanosin, Guanosin und 5'-Guanosinmonophosphat zur Aktivierung monocyclischer aromatischer Amine (z. B. Phenacetin) zu ultimaten Carcinogenen (N-aryl-O-(α-aminoacyl)hydroxylamines: model reactions with deoxyguanosine, guanosine and 5'-guanosine monophosphate for the activation of monocyclic aromatic amines (e.g. phenacetin) into ultimate carcinogens) Chris Meier, Gernot Boche Chemische Berichte 123, 1699-1705 (1990) |
| 4 |
1H- und 13C-NMR-Konformationsanalysen und Minimal-Potential-Energie-Rechnungen an Desoxyguanosin-, Guanosin- und 5'-Guanosinmonophosphat-Addukten des Grenzcarcinogens 4-Methylanilin (Proton and carbon-13 NMR-conformational analysis and minimal-potential-energy calculations with deoxyguanosine, guanosine and 5'-guanosine monophosphate adducts of the borderline carcinogen 4-methylaniline) Chris Meier, Gernot Boche Chemische Berichte 123, 1707-1713 (1990) |
| 3 |
N-(α-Aminoacyloxy)-N-arylamines: activation of aromatic amines to ultimate carcinogens by amino acids Chris Meier, Gernot Boche Tetrahedron Letters 31, 1685-1688 (1990) |
| 2 |
N-Acetoxy-4-methoxyaniline, a model compound for the ultimate carcinogen of the phenacetin-related 4-ethoxyaniline Chris Meier, Gernot Boche Tetrahedron Letters 31, 1693-1696 (1990) |
1988 | |
| 1 |
Hydrazines and azo compounds from o-diphenylphosphinoyl arylhydroxylamines Gernot Boche, Chris Meier, Wolfgang Kleemiß Tetrahedron Letters 29, 1777-1780 (1988) |
