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Universität Hamburg Fachbereich Chemie



Inhalt:

Kurzbiographie

1960 geboren in Hamburg
1996 Promotion bei Carl-Wilhelm in Hamburg
1997-1999 Wissenschaftliche Angestellte (C1), Fachbereich Chemie der Universität Hamburg, Abteilung für Biochemie und Molekularbiologie
1999-2001 Assistant Professor, Cancer Research Center of Hawaii, University of Hawaii at Manoa, USA
2001-2003 Arbeitsgruppenleiterin (C1), Fachbereich Chemie der Universität Hamburg, Abteilung für Abteilung für Biochemie und Molekularbiologie
2002 Habilitation in Hamburg
2002- Leitung Labor, Forschung und Service (Vice President Research & Services) der Indivumed GmbH, Hamburg
2003- Privatdozentin für Biochemie und Molekularbiologie an der Universität Hamburg

Weitere Informationen

Publikationen

 
2008
1 Sample preparation by laser microdissection and catapulting for proteome analysis
Karin Schütze; Andrea Buchstaller; Yilmaz Niyaz; Christian Melle; Günther Ernst; Kerstin A. David; Thorsten Schlomm; Ferdinand von Eggeling -/- Herausgeber: Jörg von Hagen
Proteomics Sample Preparation 219-234 (2008)
 
2007
2 Detection of colorectal adenoma and cancer based on transthyretin and C3a-desArg serum levels
Anne-Kristin Fentz; Monika Spörl; Jörg Spangenberg; Heinz Joachim List; Carsten Zornig; Arnulf Dörner; Peter Layer; Hartmut Juhl; Kerstin A. David
Proteomics: Clinical Applications 1, 536-544 (2007)
3 Use of endoplasmin fragment as a biomarker for colorectal adenoma and/or carcinoma
Hartmut Juhl; Kerstin A. David; Anne-Kristin Fentz
Patent: WO 2007019875 (A1) 2007-02-22
4 Use of c3a and derivatives thereof as a biomarker for benign lung tissue alterations and malignant lung tumors, method for detection and test system
Hartmut Juhl; Kerstin A. David
Patent: WO 2007065463 (A1) 2007-06-14
 
2006
5 Use of transthyretin as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
Hartmut Juhl; Kerstin A. David
Patent: WO 2006015616 (A1) 2006-02-16
6 Use of c3a and derivatives thereof as a biomarker for colorectal ademona and/or carcinoma; diagnosis method and test system using the same
Hartmut Juhl; Kerstin A. David; Anne-Kristin Fentz
Patent: WO 2006053592 (A1) 2006-05-26
 
2005
7 Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis
Thorsten Schlomm; Andreas M. Luebke; Holger Sültmann; Olaf J. C. Hellwinkel; Ulrich Sauer; Annemarie Poustka; Kerstin A. David; Felix K. H. Chun; Alexander Haese; Markus Graefen; Andreas Erbersdobler; Hartwig Huland
International Journal of Oncology 27, 713-720 (2005)
8 Detection and quantification of mutations in the plasma of patients with colorectal tumors
Frank Diehl; Meng Li; Devin Dressman; Yiping He; Dong Shen; Steve Szabo; Luis A. Diaz; Steven N. Goodman; Kerstin A. David; Hartmut Juhl; Kenneth W. Kinzler; Bert Vogelstein
Proceedings of the National Academy of Sciences of the United States of America 102, 16368-16373 (2005)
 
2004
9 Tissue ischemia time affects gene and protein expression patterns within minutes following surgical tumor excision
Annika Sprüssel; Garnet Steimann; Mira Jung; Sung A. Lee; Theresa Carr; Anne-Kristin Fentz; Jörg Spangenberg; Carsten Zornig; Hartmut H. Juhl; Kerstin A. David
BioTechniques 36, 1030-1037 (2004)
 
2002
10 Key role of mitochondria in cerulenin-mediated apoptosis
Sven Heiligtag; Reinhard Bredehorst; Kerstin A. David
Cell Death and Differentiation 9, 1017-1025 (2002)
11 Identifizierung und Charakterisierung von Apoptose-induzierenden Wirkstoffen zur Behandlung des Neuroblastom
Kerstin A. David
Habilitationsschrift, Hamburg (2002)
 
2001
12 A novel metastatic animal model reflecting the clinical appearance of human neuroblastoma: growth arrest of orthotopic tumors by natural, cytotoxic human immunoglobulin M antibodies
Sylvia Engler; Christian Thiel; Kristine Förster; Kerstin A. David; Reinhard Bredehorst; Hartmut Juhl
Cancer Research 61, 2968-2973 (2001)
13 What establishes a protein as an allergen?
Reinhard Bredehorst; Kerstin A. David
Journal of Chromatography, B: Biomedical Sciences and Applications 756, 33-40 (2001)
14 Initial characterization of the apoptosis-inducing receptor for natural human anti-neuroblastoma IgM
Kerstin A. David; Sven Heiligtag; Markus W. Ollert; M. Teppke; Carl-Wilhelm Vogel; Reinhard Bredehorst
Medical and Pediatric Oncology 36, 251-257 (2001)
 
1999
15 Human natural immunoglobulin M antibodies induce apoptosis of human neuroblastoma cells by binding to a Mr 260,000 antigen
Kerstin A. David; Markus W. Ollert; Caren Vollmert; Sven Heiligtag; Britta Eickhoff; Rudolf Erttmann; Reinhard Bredehorst; Carl-Wilhelm Vogel
Cancer Research 59, 3768-3775 (1999)
16 Natural human IgM-antibodies in neuroblastoma therapy: preliminary findings of a phase I/II clinical trial
Caroline Schmitt; Kerstin A. David; J. Hiller; J. Schrum; Reinhard Bredehorst; Carl-Wilhelm Vogel; C. Löliger; Rudolf Erttmann
Klinische Pädiatrie 211, 314-318 (1999)
 
1997
17 Expression of a 260 kDa neuroblastoma surface antigen, the target of cytotoxic natural human IgM: correlation to MYCN amplification and effects of retinoic acid
Kerstin A. David; A. Ehrhardt; Markus W. Ollert; Rudolf Erttmann; Reinhard Bredehorst; Carl-Wilhelm Vogel
European Journal of Cancer 33, 1937-1941 (1997)
18 Mechanisms of in vivo antineuroblastoma activity of human natural IgM
Markus W. Ollert; Kerstin A. David; C. Vollmert; Hartmut Juhl; Rudolf Erttmann; Reinhard Bredehorst; Carl-Wilhelm Vogel
European Journal of Cancer 33, 1942-1948 (1997)
 
1996
19 Growth arrest of solid human neuroblastoma xenografts in nude rats by natural IgM from healthy humans
Kerstin A. David; Markus W. Ollert; Hartmut Juhl; Caren Vollmert; Rudolf Erttmann; Carl-Wilhelm Vogel; Reinhard Bredehorst
Nature Medicine 2, 686-689 (1996)
20 Naturally occurring humoral cytotoxicity against neuroblastoma (NB) cells in healthy persons and NB patients
Rudolf Erttmann; Caroline Schmitt; Markus W. Ollert; Kerstin A. David; Reinhard Bredehorst; Carl-Wilhelm Vogel
Pediatric Hematology and Oncology 13, 545-548 (1996)
21 Normal human serum contains a natural IgM antibody cytotoxic for human neuroblastoma cells
Markus W. Ollert; Kerstin A. David; Caroline Schmitt; Alexander Hauenschild; Reinhard Bredehorst; Rudolf Erttmann; Carl-Wilhelm Vogel
Proceedings of the National Academy of Sciences of the United States of America 93, 4498-4503 (1996)
22 Natürliche zytotoxische Antikörper gegen humane Neuroblastom-Zellen : Analyse der zytotoxischen Mechanismen und Charakterisierung des Antigens
Kerstin A. David (= Kerstin David) -/- Betreuer: Carl-Wilhelm Vogel
Dissertation, Hamburg (1996), ISBN 978-3-928943-89-5; 3-928943-89-8, Verlag: Wissenschaft und Technik Verl. Groß, Berlin
 
1995
23 Classical complement pathway activation on nucleated cells. Role of factor H in the control of deposited C3b
Markus W. Ollert; Kerstin A. David; Reinhard Bredehorst; Carl-Wilhelm Vogel
Journal of Immunology 155, 4955-4962 (1995)
 
1994
24 Antibody-mediated complement activation on nucleated cells
Markus W. Ollert; Joseph V. Kadlec; Kerstin A. David; Eugene C. Petrella; Reinhard Bredehorst; Carl-Wilhelm Vogel
Journal of Immunology 153, 2213-2221 (1994)

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